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We report an unusual case of a patient presenting with Cushing’s syndrome caused by a phaeochromocytoma secreting adrenocorticotropic hormone (ACTH). The patient had a history of treatment-resistant hypertension, secondary amenorrhoea and tendency towards hypokalaemia. She had multiple signs of Cushing’s syndrome, such as swelling, bruising, abdominal striae and proximal myopathy. Hypokalaemia is
Brake particle emissions present significant risks to human health, particularly when they contain metallic fine particles, which can induce oxidative stress, disrupt cellular structures, and cause genetic damage. In this study, an alumina coating was deposited on cast iron discs and a non-asbestos organic (NAO) pad and a low-metallic (LM) pad (as reference) were used as counterparts of the brake
There are ongoing questions about the most effective wavelength for photobiomodulation (PBM) on major salivary glands due to the specific anatomical location and unique optical properties of the tissues surrounding the glands. The aim of this study was to analyze the photon propagation in the major salivary glands region of humans and rats using Monte Carlo (MC) stochastic simulation. Phantoms wer
Firms require multi-stakeholder ecosystems to successfully create and implement circular business models for electric vehicle (EV) battery second life. However, there is a notable absence of guiding instruments to assist EV battery ecosystem actors in formulating and managing strategies for battery second-life operations. This study's aim is to analyze how circular ecosystems are formed and manage
Background Access to adequate antenatal care (ANC) is crucial for improving maternal and neonatal health outcomes. Despite high national ANC coverage, Colombia still faces regional and socioeconomic disparities. This study aims to estimate geographical and intersectional inequalities in ANC coverage and evaluate the contribution of social determinants to these disparities. Methods We conducted a c
Transient thermoreflectance (TTR) technique is employed to study the thermal conductivity of β-Ga2O3 and high Al-content AlxGa1-xN semiconductors, which are very promising materials for high-power device applications. The experimental data are analyzed with the Callaway's model taking into account all relevant phonon scattering processes. Our results show that out-of-plane thermal conductivity of
This thesis examines how parody and satire are used in contemporary Americananimated television series. Through critical textual analysis, five television shows are examined. These are Archer, BoJack Horseman, My Little Pony: Friendship is Magic, Rick and Morty, and South Park. The study offers theoretical background and discussion on key concepts like parody, satire, comedy, animation, television
Study objectives: The impact of rapid eye movement (REM) sleep duration on long-term adherence to continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea (OSA) is unclear. This study aimed to assess the characteristics of individuals with short REM sleep and investigate whether reduced REM sleep is associated with lower CPAP adherence over a two-year period in t
This study investigates the practical integration of Building Information Modelling (BIM) and Building Energy Modelling (BEM) for energy-efficient building design. This research explores the challenges and opportunities of openBIM-to-BEM workflows by drawing on a literature review and a real-world case study in Östergötland County, typical of the Million Programme, a large public housing initiativ
“Digital participation” refers to being actively involved in the digital society and using information and communication technology, above all the internet. However, not everyone has access to this global network and the ability to use it. The aim of the study was to explore experiences of using the internet and digital participation among people with aphasia (PWA) in Sweden by analysing data from
Glucuronidation is the major phase II biotransformation reaction that facilitates the clearance of exogenous compounds from the human body. Glucuronidated metabolites have been investigated in urine samples at a broad scale; however, their characterization in other human biospecimens is underexplored. Our study has now performed a comprehensive profiling of glucuronides in plasma, fecal, and cereb
Purpose: We aimed to investigate the association between overlapping threat to fixation (TTF) and vision-related quality of life (VRQoL) in patients with manifest open-angle glaucoma (OAG). Methods: Overall, 316 patients with manifest OAG were recruited from the glaucoma outpatient department of Skåne University Hospital, Malmö, Sweden, between April and December 2018. VRQoL was assessed using the
A single zircon grain dated by ion probe with a minimum age of 3432±30 Ma was found in a microgranite dyke, which cuts norite of 916±11 Ma Hakefjorden Complex at Älgön on the Swedish west coast north of Gothenburg. Zircons are a rare accessory mineral in this dyke. They could be classified by morphology as orthocrysts and xenocrysts. Data from four orthocrysts show that the dyke originated between
Indonesia faces a severe plastic pollution crisis driven by extensive plastic usage and inadequate waste management. To effectively address this issue and promote sustainable circularity, it is crucial to understand the dynamics of plastic production, use, and end-of-life management, as well as the interactions among stakeholders throughout the plastics lifecycle. Without such a comprehensive unde
Rhesus macaques (RMs) are a vital model for studying human disease and invaluable to pre-clinical vaccine research, particularly for the study of broadly neutralizing antibody responses. Such studies require robust genetic resources for antibody-encoding genes within the immunoglobulin (IG) loci. The complexity of the IG loci has historically made them challenging to characterize accurately. To ad
This work is devoted to the development and comprehensive validation of a new interatomic potential for bcc and hcp refractory alloys based on the Wsingle bondMosingle bondNbsingle bondTasingle bondZrsingle bondTi system. The presented model allows the simulation of various structural transformations, as well as the behavior of crystal defects in several of the phases observed in this system. The
Particle packings are widely used in process applications, yet often have poor flow distribution due to random channel geometries. Regular channels can now be realised using 3D-printing, where tuneable channel morphology also offers the possibility of promoting vortices and fluctuating motion to enhance heat and mass transfer. Detailed visualisation experiments are required to understand hydrodyna
Land use change threatens global biodiversity and compromises ecosystem functions, including pollination and food production. Reduced taxonomic α-diversity is often reported under land use change, yet the impacts could be different at larger spatial scales (i.e., γ-diversity), either due to reduced β-diversity amplifying diversity loss or increased β-diversity dampening diversity loss. Additionall
Nepal has made major progress in expanding its national electricity grid, creating the potential for a double transition as increased access to electricity benefits the energy-poor while setting the infrastructural ground for a transition to renewable energy sources. However, despite increased access, many households in Nepalcontinue to rely on traditional and transition fuels such as firewood and
