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Central characteristics and critical success factors of design thinking for product development in industrial SMEs : a bibliometric analysis

Design thinking is an innovative methodology that may be applied by small and medium enterprises which emphasizes a human-centered approach to problem-solving, facilitating the creation of novel solutions for complex and open-ended challenges like the development of new products. Despite its recognized importance in business and academia, many industrial SMEs struggle with applying design thinking

Tuning Pluronic F127 phase transitions by adding physiological amounts of salts : A rheology, SAXS, and NMR investigation

Specific ion (Hofmeister) effects in colloid and biological systems represented a scientific challenge for more than 100 years. Recently, possible applications, based on their rationalization, are emerging. Here, Cl-, SO42-, SCN- anions and Na+, K+, Mg2+ cations are added at physiological concentration (∼0.15 mol/kg) to Pluronic F127 20 wt% aqueous solutions to suitably tune phase transitions for

Intergenerational care in corona times: Practices of care in Swedish families during the pandemic

Objective: This paper analyses intergenerational relationships in Sweden during the corona pandemic, with a special focus on practices of care. The research question is: How is care between generations – between grandparents, adult children and grandchildren – done during pandemic conditions? Background: In Sweden, where an extensive welfare state provides affordable child- and eldercare, the coro

Genetic factors affect the susceptibility to bacterial infections in diabetes

Diabetes increases the risk of bacterial infections. We investigated whether common genetic variants associate with infection susceptibility in Finnish diabetic individuals. We performed genome-wide association studies and pathway analysis for bacterial infection frequency in Finnish adult diabetic individuals (FinnDiane Study; N = 5092, Diabetes Registry Vaasa; N = 4247) using national register d

Postoperative prognosis in craniopharyngioma with respect to cardiovascular mortality, survival, and tumor recurrence

Specific causes of death, survival, and recurrence rates were assessed in a cohort of 60 patients who had undergone surgery for craniopharyngioma between 1951 and 1988. Compared to the general population, the standardized mortality ratio (SMR) was increased [5.55; 95% confidence interval (CI), 3.68-8.22], and it was higher among females (SMR, 11.4) than males (SMR, 4.79). The risk of cardio- and c

Seeing in the dark: vision and visual behaviour in nocturnal bees and wasps.

In response to the pressures of predation, parasitism and competition for limited resources, several groups of (mainly) tropical bees and wasps have independently evolved a nocturnal lifestyle. Like their day-active (diurnal) relatives, these insects possess apposition compound eyes, a relatively light-insensitive eye design that is best suited to vision in bright light. Despite this, nocturnal be

Motivating factors for return to work.

BACKGROUND AND PURPOSE: A new concept to increase return to work for patients listed as sick with chronic musculoskeletal pain has been used at a rehabilitation centre in Luleå, Sweden. The programme includes work for three days a week and intensive rehabilitation for two days a week, for 12 weeks, as a combination of 'on the job' training and rehabilitation after a period off work sick. The rehab

Hemodynamic impact of abdominal aortic aneurysm stent-graft implantation-induced stenosis

The current study aims to computationally evaluate the hemodynamic impact of a novel sealing mechanism employed by a recently developed endograft (Ovation TriVascular Stent-Graft System) for endovascular aneurysm repair. The exploitation of two inflatable O-rings to achieve sealing may be advantageous in terms of accommodating challenging anatomies, but comes at a price of a marked inflow stenosis

A longitudinal analysis of the relationships of physical activity and body fat with nerve growth factor and brain-derived neural factor in children

Background: Nerve growth factor (NGF) and brain-derived neural factor (BDNF) are important for brain function and detectable in the blood. This study explored the longitudinal associations of physical activity and body fat with serum NGF and BDNF in children. Methods: Two waves of measurements were performed 2 years apart in 8- to 11-year-old children, including physical activity using the ActiGra

Evaluation of the trust in physician scale (TIPS) of primary health care patients in north-east Poland : A preliminary study

Background. Trust is a complex concept, difficult to study, but very important in a patient-family physician relationship. One of the measures used to assess interpersonal trust is a scale developed by Anderson & Dedrick entitled the Trust in Physician Scale (TI PS). Objectives. The aim of the study was to assess the TI PS properties in relation to the age, gender, and health status of primary

Weight change patterns and healthcare costs in patients with newly-diagnosed type-2 diabetes in Sweden

Aims To describe weight-change pathways in patients with type 2 diabetes (T2D) and associated healthcare costs using repeated BMI measurements and healthcare utilization data. Methods Patients with newly-diagnosed T2D with body mass index (BMI, kg/m2) at diagnosis and subsequent measures at year 1–3 were identified. Based on three-year BMI change, patients were assigned to one of 27 BMI change pat

Evaluation of quality of care in relation to health-related quality of life of patients diagnosed with brain tumor : a novel clinic for proton beam therapy

Purpose: Patients with brain tumors constitute a vulnerable group, and it is important that they receive the highest quality of care (QoC). The study aim was to describe the perceptions of QoC and its association with health-related quality of life in brain tumor patients undergoing proton beam therapy in a newly established clinic. Method: Data were collected at the start of treatment and after 3

Utilizing optimal control and physical measurements when developing operator assist, automatic functions and autonomous machines

A method using optimal control results as input to operator assist systems, automatic functions and autonomous construction machine control is presented. This method complements the vast research within autonomy to achieve the most fuel efficient solution from results that are already available from concept evaluation and system optimization in early development. The optimal control results are va

97Ru-transferrin uptake in tumor and abscess

The uptake of97Ru-transferrin (Ru-TF) in tumor and abscess bearing animals was compared with67Ga-citrate (Ga),123I-transferrin (I-TF), and several other plasma proteins. Maximal concentration in tumor of Ru-TF in mice was three times higher than67Ga-citrate (16.80±4.20 vs 5.08±0.58% D/g) although it occurred later (24 h compared with67Ga which reached its maximum 2 h after injection). Whole body a

A Joint Desalination and Power Plants for Water and Development: A Case study of the Sinai-Gaza

Desalination can be a cost-effective way to produce fresh water and possibly electricity. The Gaza Strip has had a complex hydro-political situation for many years. Gaza (enclosed area) is bordered by the Mediterranean in the west, by Israel in the north and east and by Egypt in the south. Water and electricity consumption in the Gaza Strip is expected to increase in the future due to the increasi

Central nervous processing of sex pheromones in two strains of the European corn borer Ostrinia nubilalis (Lepidoptera : Pyralidae)

Antennal lobe neurones were investigated in the pyralid moth Ostrinia nubilalis using intracellular recording and staining techniques. Response characteristics of antennal lobe neurones from males in the so-called E and Z strains, in F1 hybrids and in parental backcrosses were studied. The antennal lobe of a male O. nubilalis comprises approximately 30 ordinary glomeruli and three enlarged glomeru

Effects of Injection Strategies on Fluid Flow and Turbulence in Partially Premixed Combustion (PPC) in a Light Duty Engine

Partially premixed combustion (PPC) is used to meet the increasing demands of emission legislation and to improve fuel efficiency. With gasoline fuels, PPC has the advantage of a longer premixed duration of the fuel/air mixture, which prevents soot formation. In addition, the overall combustion stability can be increased with a longer ignition delay, providing proper fuel injection strategies. In

Immunofluorometric assay for sensitive and specific measurement of human prostatic glandular kallikrein (hK2) in serum

Prostate-specific antigen (PSA) and human prostatic glandular kallikrein (hK2) have 79% identity with the primary structure. When we used recombinant hK2 protein, only 7 of 23 monoclonal anti-PSA IgGs (monoclonal antibodies, MAbs) cross-reacted with hK2, which enabled us to design a novel immunofluorometric MAb-MAb assay for the specific detection of hK2. In the first incubation, an excess of MAb

Influence of microbial species on small intestinal myoelectric activity and transit in germ-free rats

The effect of an intestinal microflora consisting of selected microbial species on myoelectric activity of small intestine was studied using germ-free rat models, with recording before and after specific intestinal colonization, in the unanesthetized state. Intestinal transit, neuropeptides in blood (RIA), and neuromessengers in the intestinal wall were determined. Clostridium tabificum vp 04 prom