Sökresultat

Context In most cases of non-islet cell tumor hypoglycemia (NICTH), high molecular weight forms of insulin-like growth factor II, commonly referred to as big IGF-II, cause hypoglycemia. MicroRNA-483 (miR-483), encoded within an intron of IGF2, has been suggested to be coexpressed with IGF-II. Objective The aim of this study is to demonstrate the utility and reliability of circulating miR-483 as a

There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen

Cytostatic pharmaceuticals are not completely removed in wastewater treatment plants (WWTPs) and may affect aquatic ecosystems. Their quantification is challenging due to variations in wastewater characteristics, which influence analytical performance. An analytical procedure has been developed, based on solid-phase extraction and liquid chromatography coupled with tandem mass spectrometry, for th

The retinoblastoma gene (RB1), which is located on chromosome 13q14.2, is mutated in retinoblastoma (RB), the most common malignant intraocular tumor in children. About 8000 new cases of retinoblastoma are diagnosed globally each year, accounting for approximately 1 in 17,000 live births. RB is prototypically considered hereditary by nature as thirty to forty percent of cases have autosomal domina

Micropollutants in wastewater can persist through conventional treatment, threatening ecosystems and human health through toxicity, bioaccumulation, and disruption of biological processes. Limited monitoring, due to cost and methodological challenges, allows these compounds to go undetected, potentially leading to long-term, irreversible impacts. To address this, modern wastewater treatment plants

Pancreatic (PC), colorectal (CRC), hepatocellular (HCC), and gallbladder (GC) cancers together account for nearly 20% of all cancer cases. However, specific biomarkers and therapeutic targets for these cancers are lacking. Diagnosing these cancers early and providing timely, appropriate treatment to improve patient outcomes is crucial. In this context, previous studies, including ours, have highli

The mitochondrial protein NAD(P) + transhydrogenase (NNT) has been implicated in the metabolic derangements observed in obesity. Mice with the C57BL/6J genetic background bear a spontaneous mutation in the Nnt gene and are known to exhibit increased susceptibility to diet-induced metabolic disorders. Most of the studies on NNT in the context of diet-induced obesity have compared C57BL/6J mice with

Dealing with the heterogeneity of breast tumors and treating breast cancer patients pose a great challenge. The heterogeneity within and between tumors indicates that each case of breast cancer may have a good prognosis and could benefit from tailored therapies. Breast cancer is a condition that undergoes changes as the tumor progresses and metastasizes, which presents further challenges for imple

Type 1 diabetes is a chronic, autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. Early detection can facilitate timely intervention, potentially delaying or preventing disease onset. Circulating proteins reflect dysregulated biological processes and offer insights into early disease mechanisms. Here, we construct a genome-wide pQTL map of 1985 protein

Stem cells are unique, undifferentiated cells that have the ability to both replicate themselves and develop into specialized cell types. This dual capability makes them valuable in the development of regenerative medicine. Current development in stem cell research has widened their application in cell therapy, drug discovery, reproductive cloning in animals, and cell models for various diseases.

Background and aim: Telomere length (TL) is a key biomarker of cellular aging, with shorter telomeres associated with age-related diseases. Lifestyle interventions mitigating telomere shortening are essential for preventing such conditions. This study aimed to examine the effects of two weight loss dietary strategies, based on a moderately high-protein (MHP) diet and a low-fat (LF) diet on TL in i

Antimicrobial peptides (AMPs), particularly host defense peptides (HDPs), have gained recognition for their role in host defense mechanisms, but they have also shown potential as a promising anticancer, antiviral, antiparasitic, antifungal and immunomodulatory agent. Research studies in recent years have shown HDPs play a crucial role in endothelial cell function and biology. The function of endot

Background: In Alzheimer’s disease (AD), the associations between tau pathology and brain atrophy and cognitive decline are well established, but imperfect. We investigate whether cerebrospinal fluid (CSF) biomarkers of biological processes (vascular, synaptic, and axonal integrity, neuroinflammation, neurotrophic factors) explain the disconnection between tau pathology and brain atrophy (brain re

Aims/hypothesis: The temporal suppression of insulin clearance after glucose ingestion is a key determinant of glucose tolerance for people without type 2 diabetes. Whether similar adaptations are observed after the ingestion of a mixed-macronutrient meal is unclear. Methods: In a secondary analysis of data derived from two randomised, controlled trials, we studied the temporal responses of insuli

untitled BEYOND TRANSITION? MEMORY AND IDENTITY NARRATIVES IN EASTERN AND CENTRAL EUROPE EDITED BY: BARBARA TÖRNQUIST-PLEWA, NIKLAS BERNSAND & ELEONORA NARVSELIUS CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY 2015 1 BEYOND TRANSITION? MEMORY AND IDENTITY NARRATIVES IN EASTERN AND CENTRAL EUROPE 2 3 BEYOND TRANSITION? MEMORY AND IDENTITY NARRATIVES IN EASTERN AND CENTRAL EUROPE Edited by: Barbara

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfecp7.pdf - 2026-06-04

Here you can read about annual working hours for researchers and assistant researchers. The provisions regarding annual working hours and standard holiday entitlement shall also apply to senior professors. Contents of the page:Annual working hoursTotal annual working hoursAttendance at the workplaceSpecial provisions in the event of teachingDistribution of work tasksWork beyond annual working hour

https://www.staff.lu.se/employment/working-hours/annual-working-hours-researchers - 2026-06-04

PowerPoint-presentation Third term options GRADUATE SCHOOL│ FACULTY OF SOCIAL SCIENCES Third Term – Several Options! Elective courses at Lund University or any other recognized university in Sweden or abroad. Internship 15 credits or 30 credits Exchange studies Coordinator Katarina Follin Remember! Your elective term is 30 credits. Elective Courses • The courses do not have to be on advanced level

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/information_meeting_feb_2016.pdf - 2026-06-04

2025 Årlig uppföljning av Lika villkorsplan för Lunds universitet 2022-2027 Sida 1 av 6 Rådet för jämställdhet och lika villkor Åsa K Nilsson, samordnare PM Diarienummer STYR 2025/1868 Datum 2025-09-19 Årlig uppföljning av Lika villkorsplan för Lunds universitet, 2022–2027 Lunds universitet har valt att ta fram en flerårig plan för jämställdhet och lika villkor för perioden 2022–2027. Planen inneh

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2026-03/2025-arlig-uppfoljning-lika-villkorsplan-lunds-universitet-2022%E2%80%932027.pdf - 2026-06-04