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In pharmaceutical biotechnology, ultrafiltration with diafiltration for recovery of fermentation products on an industrial scale is now the state-of-the-art technology. To optimise this process, DSS has developed two new concepts: (1) an optimised control system for constant permeate concentration even at varying feed streams and (2) continuous counter-current diafiltration to significantly reduce
Rescattering effects in the 3π system in the A1 region are studied with a method, which fulfils unitarity and has the proper analytic structure. Fairly small effects are obtained which confirm the result found in amplitude analyses, neglecting rescattering corrections, that the phases of the JP = 1+ amplitudes vary only very little over the A1 region. Similar results hold for the Q enhancement.
Aim: The paper addresses the classical question of possible plant survival in Iceland during the last glacial period in the light of a palaeobotanical record from northern Iceland, spanning the period 11,300-9000 BP, including the Younger Dryas stadial. We review the Late Cenozoic fossil plant record, the past debate on glacial plant refugia in Iceland, and the evidence for ice-free areas during t
To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid and breakpoints in 12q13, 12q24, and 19q13 seem to be common, with t(12;19)(q13;q13) being a recurrent translocation. Here, we report the first case of a probably benign splenic HP with chromosomal abn
The purpose of this work is to compute the autodetachment rates of the nsnp2 P-4(1/2) levels for Be-(2s2p2), Mg-(3s3p2) and Ca-(4s4p2) . Fano's configuration interaction model is implemented to compute the interaction between the discrete and continuum spaces of the wavefunction, which are determined using the multiconfiguration Hartree-Fock technique. Analysing the decay mechanism of the P-4(1/2)
The photodissociation dynamics of CH2ICH2I, CF2ICF2I, and CF2BrCF2I have been studied in solution after excitation at 266 nm. Formation of I-2 is apparent within tens of picoseconds in solutions of CH2ICH2I and CF2ICF2I in acetonitrile. but not from CF2BrCF2I, More I-2 is formed from CH2ICH2I rather than from CF2-ICF2I, as expected if the 12 formation is a result of secondary dissociation of the h
Digital breast tomosynthesis (DBT) is a promising technique to overcome the tissue superposition limitations found in planar 2D x-ray mammography. However, as most DBT systems do not employ an anti-scatter grid, the levels of scattered radiation recorded within the image receptor are significantly higher than that observed in planar 2D x-ray mammography. Knowledge of this field is necessary as par
Line-pair phantoms are commonly used for evaluating screen-film systems. When imaged digitally, aliasing effects give rise to additional periodic patterns. This paper examines one such effect that medical physicists are likely to encounter, and which can be used as an indicator of super-resolution.
Eukaryotic microbes (protists) that occupy low-oxygen environments often have drastically different mitochondrial metabolism compared to their aerobic relatives. A common theme among many of anaerobic protists is the serial loss of components of the electron transport chain (ETC). Here, we discuss the diversity of the ETC across the tree of eukaryotes and review hypotheses for how ETCs are modifie
The proper handling of alarms is crucial to automated process control. Fault Detection and Isolation techniques have been widely researched to determine such alarms. In practice, many alarms are only distractive and do not represent a fault situation. Here a toolbox, that uses an expert system called LARA, is proposed that aims to reduce the occurrence of so-called nuisance alarms. It is based on
This paper discuss the change in early design imposed by a Product-Service Systems (PSS) perspective onto the design and development phases of engineering design and how this affects the today de-facto standard of virtual modelling of product properties. The approach is exemplified via PSS situations related to aerospace and automotive industry in order to clarify “parameters of change” due to PSS
Induction hardening is a useful method for improving resistance to surface indentation, fatigue and wear that is favoured in comparison with through hardening, which may lack necessary toughness. The process itself involves fast heating by induction with subsequent quenching, creating a martensitic layer at the surface of the workpiece. In the present work, we demonstrate how to simulate the proce
In this paper, we present a study for the identification of stancerelated features in text data from social media. Based on our previous work on stance and our findings on stance patterns, we detected stance-related characteristics in a data set from Twitter and Facebook. We extracted various corpus-, quantitative- and computational-based features that proved to be significant for six stance categ
Understanding communication and signalling has long been strived for in studies of animal behaviour. Many songbirds have a variable and complex song, closely connected to territory defence and reproductive success. However, the quantification of such variable song is challenging. In this paper, we present a novel, automated method for detection and classification of syllables in birdsong. The meth
The identification of jets containing b hadrons is important for the physics programme of the ATLAS experiment at the Large Hadron Collider. Several algorithms to identify jets containing b hadrons are described, ranging from those based on the reconstruction of an inclusive secondary vertex or the presence of tracks with large impact parameters to combined tagging algorithms making use of multi-v
Objectives: Improved prediction modeling in osteoarthritis (OA) may encourage risk reduction through calculation of individual and population lifetime risks. There are currently no prediction models for hand OA. Thus, we aimed to 1) develop a prediction model for hand OA in men and 2) to contrast its discriminative performance to a prediction model for lung cancer and chronic obstructive pulmonary
