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Objective: To outline the best available method of measurement for detecting progression of osteoarthritis (OA) of the hip especially in therapeutic trials. Method A Medline search of articles related to progression of hip CA was performed. A group of experts met over a 1.5-day session to review available literature and new research. Specific questions were addressed in order to reach a consensus
The objective of this study was to analyze the accumulated effects of leaching in two test roads were municipal solid waste incineration (MSWI) bottom ash and aggregate from a railway embankment, respectively, were used as subbase aggregates. Solid samples from the subbase and the subgrade were collected in trenches, which were excavated perpendicular to the road extension. The samples were analyz
Ectomycorrhizae are formed by mutualistic interactions between fungi and the roots of woody plants. During symbiosis the two organisms exchange carbon and nutrients in a specific tissue that is formed at the contact between a compatible fungus and plant. There is considerable variation in the degree of host specificity among species and strains of ectomycorrhizal fungi. In this study, we have for
The mechanisms of regioselective reductive openings of acetals were investigated in several model systems by a combination of Hammett plots, kinetic experiments, density functional calculations, and B-11 NMR. The regioselectivity of borane reductions of cyclic acetals can be controlled by the choice of borane. Lewis acid activation of BH3 center dot NMe3 increases the reaction rate and renders the
The effect of temperature and enzyme concentration on the enzymatic hydrolysis of steam-pretreated willow was investigated to obtain the optimal hydrolysis conditions. The willow was pretreated at 220°C for 10 min according to the results of earlier optimization studies of the steam-pretreatment conditions for high glucose yields. The concentrations of two commercial enzymes, Celluclast 2L and Nov
Hormonal cancers such as breast and prostate cancer arise from steroid hormone-regulated tissues. In addition to breast and prostate cancer hormonal regulation has also a role in endometrial, ovarian, testis and thyroid carcinomas. The effects of estrogens, androgens and progestagens on tumor growth are largely mediated by paracrine and autocrine target molecules which include growth factors and g
Immunization of mice with type II collagen (CII), a cartilage-restricted protein, leads to collagen-induced arthritis (CIA), a model for rheumatoid arthritis (RA). CIA symptoms consist of an erosive joint inflammation caused by an autoimmune attack, mediated by both T and B lymphocytes. CD4+ alphabeta T cells play a central role in CIA, both by helping B cells to produce anti-CII antibodies, and b
Background: Many studies have been conducted on the accuracy of prenatal ultrasound diagnosis of foetal CNS-malformations. These studies were mostly hospital-based or, sometimes, multicentre studies. We present here a population-based study of the prenatal diagnosis of spina bifida in Sweden over a period of 31 years. Methods: We compared the number of newborns with spina bifida and the elective t
Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two highly allergenic compounds used in the chemical industry. A method was developed for quantification of protein adducts of HHPA and MHHPA in human plasma. The plasma was dialysed and the anhydrides were hydrolysed from the proteins at mild acidic conditions. The released hexahydrophthalic acid (HHP acid) and m
Tendon injuries at the epicondyle can occur in athletes and workers whose job functions involve repetitive, high force hand activities, but the early pathophysiologic changes of tendon are not well known. The purpose of this study was to evaluate early tendon structural changes, specifically the formation of microtears, caused by cyclical loading. The Flexor Digitorum Profundus (FDP) muscle of nin
SIR—Older people with mobility limitations often report more barriers in their outdoor environment than people with intact mobility [1]. However, it is uncertain whether older people perceive their environment as problematic because of their mobility limitations or whether the environmental barriers precede incident mobility limitation, as most studies have been limited to cross-sectional analyses
We have investigated, comparatively, the ontogenetic development of the compound eye in larvae of a mysid (Neomysis) and a euphausiid (Thysanoessa) species and found it to be close to identical in the two species. The larval eye is of apposition type with special adaptations for planktonic life. The elongated dioptric apparatus is devoid of screening pigment and instead has a proximal lens optical
A novel pilot-control globe valve, which can be used in vertical pipelines with a lower driving energy consumption, is proposed. A governing equation for valve core motion is obtained through a theoretical analysis of the forces applied on the valve core. A 3D simulation of valve core motion is conducted in Fluent by using User Defined Function (UDF) to involve different spring stiffness, steady s
Mesocrystals composed of crystallographically aligned nanocrystals are present in biominerals and assembled materials which show strongly directional properties of importance for mechanical protection and functional devices. Mesocrystals are commonly formed by complex biomineralization processes and can also be generated by assembly of anisotropic nanocrystals. Here, we follow the evaporation-indu
The sensory axons of the adult frog sciatic nerve have earlier been shown to regenerate in vitro. If a local test crush is made at the initiation of culturing, regeneration starts after 3.4 days and proceeds at a rate of about 0.8-0.9 mm/day for several days. In the present experiments regeneration was inhibited by adenosine in a reversible and dose-dependent fashion. Similarly, both an adenosine
Neck-banded Greylag Geese Anser anser breeding in southwest Sweden were studied from 1984–2012 inclusive, to determine annual variation in the number of breeding pairs, reproductive success and survival rates, as part of a larger programme of monitoring individual geese across the Nordic countries. Numbers breeding in the study area increased from 120 pairs in 1984 to 1,240 pairs in 2008, followed
The Whooper Swan Cygnus cygnus was a rare breeding species in Sweden during the early years of the 20th century, when total numbers likely consisted of only 20 pairs. Recent decades have however seen a marked increase in numbers and a spread in the swans’ distribution, with the number of pairs breeding in the two northernmost provinces rising from 310 to 2,700 pairs between two main surveys, in 19
Regular goose counts have been undertaken in Swedensince 1977/78 as a part of the International Goose Countsorganised by Wetlands International. The main counts areundertaken in October and November, covering all sites ofimportance for Bean Goose Anser fabalis and in Januarywhen all sites are covered. September counts of GreylagGoose Anser anser will be published separately. In October,the major p
The aim of this study was to explore primary healthcare patients' experiences of patient participation prior to multimodal pain rehabilitation. Data was collected from interviews with 17 patients, aged 23-59 years, after completing multimodal rehabilitation. Data was analysed using qualitative content analysis. The theme, In search of recognition, depicted patient participation prior to the multim
