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Equalising sensor energy and maximizing sensor network lifespan using RETT

Lately, sensor networks have received much attention in the research community. One of the aims of these networks is to make them self-configuring and self-healing so that they can be easily deployed and self-sufficient. A fundamental limitation with sensor networks is their limited life span because of their battery operation. To that end, much research has been carried out to maximize the life s

Current progress of adhesins as vaccine candidates for Moraxella catarrhalis

Moraxello catorrhalis is an emerging pathogen and all isolates are now considered beta-lactamase producing. Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. catarrhalis might be thrust further into the limelight. However, a vaccine has not yet been designed. In this review, the progress of M. catarrhalis adhesins as vaccine can

A texture analysis approach to quantify ventilation changes in hyperpolarised ³He MRI of the rat lung in an asthma model

In preclinical research, allergic asthma is investigated in rats sensitised with the antigen ovalbumin (OVA), followed by a challenge with aerosolised OVA to induce an inflammatory reaction of the lower airways. This causes diffuse, nonfocal ventilation defects that lead to heterogeneously distributed signal intensities in hyperpolarised (HP) (3)He MR images, which are difficult to assess directly

Gastrectomy causes bone loss in the rat: is lack of gastric acid responsible?

Total gastrectomy or resection of the acid-producing part of the stomach (fundectomy) in the rat induced a marked and rapid reduction in bone wet weight, ash weight, and density (expressed as ash weight in mg/mm3 bone). Bone volumes were also affected but not as much. The radius, sternum, tibia, and femur were studied. Three weeks after gastrectomy the bone ash weight was reduced by almost 30% and

Plant size affects mutualistic and antagonistic interactions and reproductive success across 21 Brassicaceae species

Plant size has been hypothesized to be a major driver of biotic interactions. However, it is little understood how plant size affects plant mutualists vs. antagonists and the plant's resulting reproductive success. We established a common garden experiment covering an interspecific plant size gradient (from 10 to 130 cm height) across 21 annual Brassicaceae species, thereby standardizing features

HIV-2 Neutralization Sensitivity in Relation to Co-Receptor Entry Pathways and Env Motifs

HIV-2, compared to HIV-1, elicits potent and broadly neutralizing antibodies, and uses a broad range of co-receptors. However, both sensitivity to neutralization and breadth of co-receptor use varies between HIV-2 isolates, and the molecular background is still not fully understood. Thus, in the current study, we have deciphered relationships between HIV-2 neutralization sensitivity, co-receptor u

Systems Approach to Scaling-Up Global Upcycling : Framework for Empirical Research

Global urbanisation, increasing population, economic growth and development have caused increase in resource consumption, and consequently, a vast volume of waste and other negative environmental impacts. In order to reduce negative environmental impact, various approaches to resource management have been suggested and implemented in the system of production, consumption and waste management. One

Occupational balance in parents of pre-school children : Potential differences between mothers and fathers

Background: Parents of young children are a vulnerable group with an increased risk of stress-related health problems compared to adults without children. Low occupational balance has been identified as a risk factor for stress-related disorders. Aim: The study aimed to describe occupational balance in parents of pre-school children and to explore potential differences between mothers and fathers.

True infection or contamination in patients with positive Cutibacterium blood cultures-a retrospective cohort study

Cutibacterium is a genus often considered a contaminant when present in blood cultures, but it can also cause severe infections, especially related to implanted foreign materials. We investigated the incidence and features of patients with true Cutibacterium infection. Patients with positive Cutibacterium blood cultures between the years 2015-2020 in southern Sweden were identified through microbi

Column separation of monocytes by adherence to gelatin beads

This investigation was performed to study whether the efficient binding of collagen to monocytes in the presence of fibronectin and heparin may be used for separation of monocytes from human peripheral blood. It was shown that monocytes adhere selectively to gelatin bead columns in the presence of fresh plasma and heparin. Mononuclear blood cells are rapidly depleted of monocytes by passage throug

The ABC of happiness : Validation of the tridimensional model of subjective well-being (affect, cognition, and behavior) using Bifactor Polytomous Multidimensional Item Response Theory

Background: Happiness is often conceptualized as subjective well-being, which comprises people's evaluations of emotional experiences (i.e., the affective dimension: positive and negative feelings and emotions) and judgements of a self-imposed ideal (i.e., the cognitive dimension: life satisfaction). Recent research has established these two dimensions as primary parts of a higher order factor. Ho

Cytogenetic methods

This chapter outlines the methods currently employed in cancer cytogenetics, spanning from chromosome banding to array- and sequencing-based techniques. A correct sampling procedure is the basis for correct scientific and diagnostic conclusions. Chromosome preparation requires live cells, whereas in situ hybridization at least requires intact nuclei, and genome arrays as well as sequencing rely on

Effect of exogenous glutamate and N-Methyl-D-aspartic acid on spontaneous activity of isolated human ureter

OBJECTIVES: While the neurotransmitter role of glutamate in the gastrointestinal tract has been shown, its effects on smooth muscle of the human ureter have not previously been investigated. In our study we have investigated the effects of exogenous glutamate on the spontaneous activity of isolated human ureter, taken from 14 adult patients after nephrectomy.METHODS: The segment of ureter, excised

Patient-reported outcome measures for hip-related pain : A review of the available evidence and a consensus statement from the International Hip-related Pain Research Network, Zurich 2018

Hip-related pain is a well-recognised complaint among active young and middle-aged active adults. People experiencing hip-related disorders commonly report pain and reduced functional capacity, including difficulties in executing activities of daily living. Patient-reported outcome measures (PROMs) are essential to accurately examine and compare the effects of different treatments on disability in

Effect of intensive training on lower leg structural strength: an in vivo study in ovariectomized rats

The aim of this study was to investigate the effect of training on the in vivo tibial structural strength during the development of post-ovariectomy osteoporosis. Seventeen mature Wistar rats (215 g) were ovariectomized and randomized into two groups. The sedentary control group was kept cage confined, while 3 days postoperatively the trained group started treadmill running with high intensity for

Angular dispersion and temporal change of femtosecond pulses from misaligned pulse compressors

A misaligned stretcher or compressor in a chirped pulse amplification laser introduces residual angular dispersion into the beam, resulting in temporal distortion of the pulse. We demonstrate that an imaging spectrograph is capable for Measuring the angular dispersion of a laser beam by an accuracy of 0.2 murad/min. Using this technique, the analytical expressions of residual angular dispersion of

CD44/CD70 blockade and anti-CD154/LFA-1 treatment synergistically suppress accelerated rejection and prolong cardiac allograft survival in mice.

Current treatments that are efficient in controlling effector T cells responses to allografts have limited efficacy on the accelerated rejection mediated by memory T cells. Effective targeting of alloreactive memory T cells may therefore be explored to improve therapeutic approaches towards solving this problem. In this study, we investigated the synergistic effect of CD44/CD70 blockade and anti-C

From (p)ppGpp to (pp)pGpp : Characterization of regulatory effects of pGpp synthesized by the small alarmone synthetase of Enterococcus faecalis

The bacterial stringent response (SR) is a conserved stress tolerance mechanism that orchestrates physiological alterations to enhance cell survival. This response is mediated by the intracellular accumulation of the alarmones pppGpp and ppGpp, collectively called (p)ppGpp. In Enterococcus faecalis, (p)ppGpp metabolism is carried out by the bifunctional synthetase/hydrolase E. faecalis Rel (RelEf)