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An improved understanding of past interactions between terrestrial vegetation and various forcings, such as climate change, human impact, and paleofire, is crucial for assessing impacts of future global change on terrestrial ecosystems. This study seeks to find the key factor or factors that have driven Holocene vegetation change along the East Asian monsoon margin. Several high-resolution pollen
Every day we perform several recurring activities with little or no guidance from conscious intention. These daily and repetitive actions are often referred to as habits. The situation with Covid-19 has had a dramatic impact on how we go about our daily lives and how we interact with other persons at home or at work. In relation to working life one specific aspect was that many office workers were
AIM: SYT11 and SYT13, two calcium-insensitive synaptotagmins, are downregulated in islets from type-2 diabetic donors, but their function in insulin secretion is unknown. To address this, we investigated the physiological role of these two synaptotagmins in insulin secreting cells.METHODS: Correlations between gene expression levels were performed using previously described RNA-seq data on islets
Our study aims to increase the understanding about the impacts of potential drivers of pollen richness by using a pollen-vegetation modelling approach. We used the Sutton-Prentice dispersal model implemented in the HUMPOL software suite to explore the effects of factors commonly associated with pollen richness: vegetation diversity (plant richness and evenness), land-cover characteristics (patch r
Tropical mountain cloud forests (TMCF) harbour a high bryophyte (mosses and liverworts) biomass and diversity. Furthermore, the high air humidity makes these forests well suited for bryophyte-associated nitrogen (N2) fixation by cyanobacteria, providing a potentially important source of N input to the ecosystem. However, few studies have assessed bryophyte-associated N input in these ecosystems, a
BACKGROUND: The aim of this study is to evaluate if ilio-femoral calcium score (CS) combined with Glasgow Aneurysm Score (GAS) can improve the prediction of long-term survival after EVAR.METHODS: All the patients who underwent infrarenal endovascular aortic repair (EVAR) for non-ruptured AAA between January 2004 and December 2012 at a tertiary referral center were retrospectively included if the p
The Black Death (1347–1352 ce) is the most renowned pandemic in human history, believed by many to have killed half of Europe’s population. However, despite advances in ancient DNA research that conclusively identified the pandemic’s causative agent (bacterium Yersinia pestis), our knowledge of the Black Death remains limited, based primarily on qualitative remarks in medieval written sources avai
Wood formation determines major long-term carbon (C) accumulation in trees and therefore provides a crucial ecosystem service in mitigating climate change. Nevertheless, we lack understanding of how species with contrasting wood anatomical types differ with respect to phenology and environmental controls on wood formation. In this study, we investigated the seasonality and rates of radial growth a
Permafrost degradation poses serious threats to both natural and human systems through its influence on ecological–hydrological processes, infrastructure stability, and the climate system. The Arctic and the Third Pole (Tibetan Plateau, TP hereafter) are the two northern regions on Earth with the most extensive permafrost areas. However, there is a lack of systematic comparisons of permafrost char
Background: The majority of individuals with dementia will suffer from behavioral and psychological symptoms of dementia (BPSD). These symptoms contribute to functional impairment and caregiver burden. Objective: To characterize BPSD in Alzheimer's disease (AD), vascular dementia (VaD), mixed (Mixed) dementia, Parkinson's disease dementia (PDD), dementia with Lewy bodies (DLB), frontotemporal deme
Unisexual bryophytes provide excellent models to study the mechanisms that regulate the frequency of sexual versus asexual reproduction in plants, and their ecological and evolutionary implications. Here, we determined sex expression, phenotypic sex ratio, and individual shoot traits in 242 populations of the cosmopolitan moss Pseudoscleropodium purum spanning its whole distributional range. We te
For regions that are deeply integrated into the global economy, the question of how to remain competitive and resilient in times of uncertainty is a key concern. While strategic coupling is a useful concept for understanding local-global economic dynamics, the idea that a region can simultaneously couple into multiple production networks organised at different spatial scales and that regional acto
Sedimentary charcoal records are widely used to reconstruct regional changes in fire regimes through time in the geological past. Existing global compilations are not geographically comprehensive and do not provide consistent metadata for all sites. Furthermore, the age models provided for these records are not harmonised and many are based on older calibrations of the radiocarbon ages. These issu
Objective: The objective of this paper is to describe the initial phase of a long-term collaboration initiative between a municipality and the Faculty of Medicine at a university in Sweden. The overall ambition of the collaboration is to strengthen the quality of care for older people. The concrete goal is to equip academically trained registered health care professionals (HCP) with tools for tran
Arctic and subarctic areas have experienced a rapid warming and substantial increases in precipitation in recent decades. The frequency and intensity of some extreme events, such as fires, winter warming events, extreme rainfall, and droughts, has also increased. These climatic changes and other anthropogenic factors have caused profound changes in arctic and subarctic ecosystems with important im
Many time-series smoothing methods can be used for reducing noise and extracting plant phenological parameters from remotely-sensed data, but there is still no conclusive evidence in favor of one method over others. Here we use moderate-resolution imaging spectroradiometer (MODIS) derived normalized difference vegetation index (NDVI) to investigate five smoothing methods: Savitzky-Golay fitting (S
We present two novel earth observation products derived from the BESD and EMMA XCO2 products which were respectively retrieved from SCIAMACHY and GOSAT observations within the GreenHouse Gas project of ESA's Climate Change Initiative (GHG-CCI). These products are inferred by a Carbon Cycle Data Assimilation System (CCDAS) and consist of net and gross biosphere-atmosphere fluxes of carbon dioxide o
To study global nitrogen (N) leaching from natural ecosystems under changing N deposition, climate, and atmospheric CO2, we performed a factorial model experiment for the period 1901-2006 with the N-enabled global terrestrial ecosystem model LPJ-GUESS (Lund-Potsdam-Jena General Ecosystem Simulator). In eight global simulations, we used either the true transient time series of N deposition, climate
Purpose: This study explored whether complement factor 3 (C3) in plasma is associated with incidence of diabetes in a population-based cohort. We also identified genetic variants related to C3 and explored whether C3 and diabetes share common genetic determinants.Methods: C3 was analyzed in plasma from 4368 nondiabetic subjects, 46 to 68 years old, from the Malmö Diet and Cancer Study. Incidence o
Rhombomys opimus (R. opimus), a social rodent, is the main reservoir host for zoonotic cutaneous leishmaniasis (ZCL) in most parts of the Middle East and central Asia. The difficulties in monitoring rodent population patterns have hindered the effective application of preventive measures of ZCL. This study presents a spatially explicit agent-based simulation model of R. opimus behaviors that is in
