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AIMS: To study HLA-DQB1 genes and islet cell autoantibodies against glutamic acid decarboxylase 65 (GADA) and insulinoma antigen-2 (IA-2A) in relation to diabetes post partum in mothers with diagnosed gestational diabetes mellitus (GDM). METHODS: During 2003-2004, women undergoing a 75g oral glucose tolerance test (OGTT) during pregnancy were invited to participate in the Mamma Study. Cut-off leve
Background: p-tert-Butylphenol-formaldehyde resin (PTBP-FR) is a common component of glues used in the manufacturing of many plastic, electronic, rubber, wood, and leather products. Two main allergens of PTBP-FR have been described. Objectives: The objective of this study is to determine the concentrations of the two main allergens of PTBP-FR in diagnostic patch testing preparations and PTBP-FR av
A method is presented in which fracture mechanics is introduced into finite element analysis by means of a model where stresses are assumed to act across a crack as long as it is narrowly opened. This assumption may be regarded as a way of expressing the energy adsorption GC in the energy balance approach, but it is also in agreement with results of tension tests. As a demonstration the method has
This paper presents arguments for a re-analysis of the b-prefix in Gulf Arabic dialects. Similar to several other dialects, Gulf Arabic possesses a b-prefix that is inserted before the p-stem (prefix form) of the verb. However, the Gulf Arabic b-prefix differs substantially from the one encountered in other Arabic dialects. According to most previous studies, the Gulf Arabic b-prefix encodes futur
The purpose of this study was to illuminate the everyday experience of family members 3 years after a child had been diagnosed as having Type 1 diabetes. Qualitative interviews were conducted with 35 family members in 11 families and analyzed using a content analysis. The results were identified as eight categories describing the family member's everyday experiences: (a) knowledge and tried experi
The authors examine the effect of the core hole on several spectroscopies used to explore the conduction band of simple metals. They show that the static effect on the valence electrons is very strong and discuss under what circumstances this effect may be seen experimentally. In KLV Auger spectra a core hole is present in both initial and final states. Thus, there will be almost no dynamical effe
AIMS/HYPOTHESIS: The T allele of transcription factor 7-like 2 gene variant, TCF7L2 rs7903146, increases the risk of type 2 diabetes by 40-50%. As TCF7L2 rs7903146 has been associated with diminished incretin effect we investigated whether interaction between dietary intake of carbohydrate, fat, protein or fibre and this variant affects the risk of type 2 diabetes. METHODS: A cohort of 24,799
As several studies have provided evidence that lung disease affects the T1 of the human lung, our purpose was to investigate the effect of age on the T1-relaxation time in the lungs of healthy never-smokers, including group difference between sexes.
The resonance lines in Li I and Na I both exhibit a puzzling discrepancy between experiment and accurate ab initio calculations. Only results from a semiempirical method, that in principal neglects core-core correlation, agree with the experiments. The agreement with a multiconfiguration Hartree-Fock calculation, including only core-valence correlation, shows that this might be fortuitous. A metho
The initiating somatic genetic events in chordoma development have not yet been identified. Most cytogenetically investigated chordomas have displayed near-diploid or moderately hypodiploid karyotypes, with several numerical and structural rearrangements. However, no consistent structural chromosome aberration has been reported. This is the first array-based study characterising DNA copy number ch
We evaluated whether matrix metalloproteinases (MMPs) 2 and 9, their inhibitors, markers for fibrinolysis, and thrombin activation are associated with diameter and growth of abdominal aortic aneurysms (AAAs). Material and Methods: Matrix metalloproteinases 2 and 9, tissue inhibitor of MMPs (TIMP-1), serpine-1, tPa-serpine-1, and activated protein C- protein C inhibitor (APC-PCI) complex were analy
The development of L-DOPA-induced dyskinesia (LID) is attributed to plastic responses triggered by dopamine (DA) receptor stimulation in the parkinsonian brain. This article reviews studies that have uncovered different levels of maladaptive plasticity in animal models of LID. Rats developing dyskinesia on chronic L-DOPA treatment show abnormal patterns of signaling pathway activation and synaptic
Lumbar puncture (LP) is increasingly performed in memory clinics. We investigated patient-acceptance of LP, incidence of and risk factors for post-LP complications in memory clinic populations.
To examine age at onset of substance abuse in relation to other factors of relevance to criminal behavior, we compared Life History of Aggression (LHA) scores, traits of psychopathy according to the Psychopathy Checklist--Revised (PCL-R), and violent recidivism in 100 violent offenders with early (before the age of 18) versus late onset of abuse or dependence. Of 56 subjects with a history of alco
Objective: To examine how well ultrasound assessed occipitoposterior (OP) position or high sagittal (HS) position in primiparous women with a prolonged first stage of labor predicts a vaginal delivery and the duration of labor. Design: Prospective observational study. Setting. Stavanger University Hospital, a secondary referral center in Norway. Population. 105 primiparous women with prolonged f
Background: Genetic polymorphisms associated with common aetiologically complex diseases have recently been identified through genome-wide association studies. Direct-to-consumer genetic testing for such polymorphisms, with provision of absolute genetic risk estimates, is marketed by several commercial companies. Polymorphisms associated with atrial fibrillation (AF) have shown relatively large r
The objective of this study is to assess the heavy metals pollution and microbial contamination in water, sediments and fish of Lake Manzala and study the direct and indirect effect for disposal of waste water, industrial and agricultural drainage water into the lake on the environmental situation. Samples were collected from four different sites in the lake and one site in the drain. The selected
