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This paper introduces a number of advancements of our recently proposed model of atrioventricular (AV) node function during atrial fibrillation (AF). The model is defined by parameters characterizing the arrival rate of atrial impulses, the probability of an impulse choosing either one of the two AV nodal pathways, the refractory periods of these pathways, and their prolongation. In the updated mo

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Ambitions and ClarificationsThe book takes its point of departure in the "intimate visions of society" that are significant of contemporary social life. This concept refers to the tendency to apprehend good social relations as personal, close and warm, while bad relations correspondingly are perceived as impersonal, cold, distant and alienated. Exemplary categories, such as closeness, warmth, commAmbitions and ClarificationsThe book takes its point of departure in the "intimate visions of society" that are significant of contemporary social life. This concept refers to the tendency to apprehend good social relations as personal, close and warm, while bad relations correspondingly are perceived as impersonal, cold, distant and alienated. Exemplary categories, such as closeness, warmth, comm

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A numerical study is performed to investigate the effects of various discrete rib configurations on the heat transfer and fluid flow characteristics of a rotating rectangular straight channel (aspect ratio of 2:1) with 45° orientation. Three parameters of the discrete rib configuration - rib streamwise distance, rib widthwise distance, and inner-half-rib angle - are examined based on a continuous

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In many species of phytoplankton, simple photoreceptors monitor ambient lighting. Photoreceptors provide a number of selective advantages including the ability to assess the time of day for circadian rhythms, seasonal changes, and the detection of excessive light intensities and harmful UV light. Photoreceptors also serve as depth gauges in the water column for behaviors such as diurnal vertical m

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PURPOSE: Retinal ganglion cells (RGCs) are exposed to injury in a variety of optic nerve diseases including glaucoma. However, not all cells respond in the same way to damage and the capacity of individual RGCs to survive or regenerate is variable. In order to elucidate factors that may be important for RGC survival and regeneration we have focussed on the extracellular matrix (ECM) and RGC integr

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A Fourier analysis of the magnitudes and timing of the Phanerozoic mass extinctions (MEs) demonstrates that many of the periodicities claimed in other analyses are not statistically significant. Moreover we show that the periodicities associated with oscillations of the Solar System about the galactic plane are too irregular to give narrow peaks in the Fourier periodograms. This leads us to conclu

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On the basis of the GBD (Global Burden of Disease) 2013 Study, this article provides an overview of the global, regional, and country-specific burden of stroke by sex and age groups, including trends in stroke burden from 1990 to 2013, and outlines recommended measures to reduce stroke burden. It shows that although stroke incidence, prevalence, mortality, and disability-adjusted life-years rates

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Harvesting of wood for bioenergy purpose will probably increase in importance in the future, in order to replace fossil fuel. However, the environmental impact of increased harvesting might be considerable, e.g. on soil and water chemistry, biodiversity and long-term productivity, and in this study we investigate thresholds for sustainable harvesting volumes. The study is based on scientific revie

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Objectives: Accurate and reliable diagnostics are crucial as histopathological type influ-ences selection of treatment in lung cancer. The aim of this study was to evaluate real-world accuracy and use of immunohistochemical (IHC) staining in lung cancer diagnostics. Materials and Methods: The diagnosis and used IHC stains for small specimens with lung cancer on follow-up resection were retrospecti

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In a non-negligible number of patients with metastatic colorectal cancer (mCRC), the peritoneum is the predominant site of dissemination. Cure can be achieved by cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), but this procedure is associated with long-term morbidity and high relapse rates. Thus, there is a pressing need for improved therapeutic strategies and co

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Eulerian stochastic fields (ESF) based transported PDF method has evolved as one of the general purpose methods for the numerical simulation of complex chemically reactive turbulent flows in which the effect of turbulence on the chemical reaction rates can be computed directly without the need of modeling. It is found that ESF method may suffer from violation of the element mass conservation law d

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Albert-László Barabási, from the introduction to his book titled Linked: the new science of networks, “Just as diverse humans share skeletons that are almost indistinguishable, we have learned that these diverse maps follow a common blueprint. A string of recent breathtaking discoveries has forced us to acknowledge that amazingly simple and far-reaching natural laws govern the structure and evolut

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Motion-event typology has moved into a “post-Talmian” terrain of approaches focusing on an open-ended number of patterns across languages and construc- tions. Following a proposal to distinguish between four typological clusters, we systematically compared the motion event descriptions in four languages suggested to exemplify these clusters: Swedish, French, Thai and Telugu, with the help of an el

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We describe 22 examples of a novel, usually paratubal, adnexal tumor associated with Peutz-Jeghers syndrome in nearly 50% of cases that harbored STK11 alterations in all tested (n=21). The patients ranged from 17 to 66 years (median=39 y) and the tumors from 4.5 to 25.5 cm (median=11 cm). Most (n=18) were paratubal, with metastases noted in 11/22 (50%) and recurrences in 12/15 (80%). Morphological

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Purpose: The purpose of this study is to investigate the effects of film holes’ arrangements and jet Reynolds number on flow structure and heat transfer characteristics of jet impingement conjugated with film cooling in a semicylinder double wall channel. Design/methodology/approach: Numerical simulations are used in this research. Streamlines on different sections, skin-friction lines, velocity,

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Thanks to name statistics published by the national bureaus of statistics in Scan­dinavia it is possible to study the changing popularity of first names. This paper is based on statistics from the years 1998-2002 in Sweden, 1998-2000 in Finland and 1880-2000 in Norway. The rise and fall in popularity — and in some cases renaissance — of individual names are shown and analyzed.It is observed that

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Histopathology Analysis of sentinel node biopsy - a single-institution experience supporting the use of serial sectioning and immunohistochemistry for detection of micrometastases by comparing four different histopathological laboratory protocols Aims:  Detecting micrometastases (>0.2 and ≤2 mm/>200 cells) and isolated tumour cells (ITCs; ≤0.2 mm/<200 cells) is important for staging of breast canc