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Series of fast synchrotron X-ray tomographies are taken continuously at a rate of up to 5Hz, while aluminium alloy precursors are foamed in an X-ray transparent setup for several minutes using infra-red (IR) lasers for heating. The entire foaming process from the solid precursor to the expanded liquid foam is captured. The analysis of the sequence of tomographies is done with an emphasis on nuclea
Familial risks of breast cancer (BC) are well established but whether BC clusters with other, i.e. discordant, cancers is less certain but of interest for the identification of common genetic and possible environmental factors contributing to a general cancer susceptibility. We apply a novel approach to search for familial associations of BC with other (discordant) cancers based on the Swedish Fam
The effects of fuel properties on the performance and emissions of an engine running in partially premixed combustion mode were investigated using nine test fuels developed in the gasoline boiling point range. The fuels covered a broad range of ignition quality and fuel chemistry.The fuels were characterized by performing a load sweep between 1 and 12 bar gross IMEP at 1000 and 1300 rpm. A heavy d
Background: Analyzing Body Mass Index as a didactical example, the study by Evans, Williams, Onnela, and Subramanian (EWOS study) introduce a novel methodology for the investigation of socioeconomic disparities in health. By using multilevel analysis to model health inequalities within and between strata defined by the intersection of multiple social and demographic dimensions, the authors provide
Purpose: To present data from an interim analysis of a Phase II trial designed to determine the feasibility, safety, and efficacy of individualising treatment based on renal dosimetry, by giving as many cycles as possible within a maximum renal biologically effective dose (BED). Method: Treatment was given with repeated cycles of 7.4 GBq 177Lu-DOTATATE at 8-12-week intervals. Detailed dosimetry wa
A pocket cavity is generated when the Low Pressure Turbine (LPT) is connected to the Outlet Guide Vane (OGV) in the rear part of a gas turbine engine due to the different conjugate diameters. This kind of pocket cavities, due to the high Reynolds number and the specific shapes, are hardly investigated in previous researches. The heat transfer distribution and fluid flow over the pocket cavity have
The paper presents a Matlab toolbox for simulation of real-time control systems. The basic idea is to simulate a real-time kernel in parallel with continuous plant dynamics. The toolbox allows the user to explore the timely behavior of control algorithms, and to study the interaction between the control tasks and the scheduler. From a research perspective, it also becomes possible to experiment wi
Lesions of ERBB2, PTEN, and PIK3CA activate the phosphatidylinositol 3-kinase (PI3K) pathway during cancer development by increasing levels of phosphatidylinositol-3,4,5-triphosphate (PIP(3)). 3-Phosphoinositide-dependent kinase 1 (PDK1) is the first node of the PI3K signal output and is required for activation of AKT. PIP(3) recruits PDK1 and AKT to the cell membrane through interactions with the
Negotiated agreements are policy instruments that are increasingly used to manage environmental issues across a range of contexts. At their simplest, negotiated agreements are contractual arrangements between public authorities and an industry that the authorities have targeted to improve their environmental aspects. Part of the attraction of these agreements are the flexibility in their design, a
The current status of overexploited fish stocks worldwide and increasing stakeholder expectations that retailers should responsibly source products have led to an increasing number of food retailers committing to sell sustainable seafood. Yet, the complexity and variety of seafood supply chains and the challenge inherent in the verification of sustainability qualities suggest that the implementati
I den svenska brottmålsprocessen intar målsäganden en förhållandevis stark ställning. Målsäganden har, under ett antal i lagen stadgade förutsättningar, rätt till ett processrättsligt deltagande i brottmålsprocessen. Genom en subsidiär åtalsrätt har målsäganden tillerkänts en rätt att föra enskilt åtal när åklagaren beslutar att inte väcka allmänt åtal. För ett begränsat antal brott har målsägande
This small-scale experiment was a first attempt at testing the theoretical framework of Processability Theory (PT), a well-established theory of Second Language Acquisition (SLA), against data from online brain imaging technology (Electroencephalography – EEG). Event Related Potentials (ERPs) were extracted for 15 advanced beginners/intermediate-level learners of Swedish who were presented with gr
The availability of dual energy X-ray absorptiometry (DXA) varies markedly in different countries. There is, however, little information to indicate the optimal requirements for this technology. The principal aim of this study was to estimate the requirements for DXA in Europe for the assessment and treatment of osteoporosis. Three assessment scenarios were chosen. The first envisaged screening of
Objectives. To evaluate the relationship between anti-neutrophil cytoplasmic antibody (ANCA) measured with two different methods and long-term clinical course in vasculitis. Design. Retrospective determination of ANCA with two different assays for detection of PR3-ANCA, conventional direct binding ELISA and capture ELISA using monoclonal antibodies against PR3. The 245 ANCA determinations were per
Aim To identify clinical, immunological and biochemical factors that predict remission, and its duration in a large cohort of young adults with Type 1 diabetes mellitus (DM). Methods In Sweden 362 patients (15-34 years) classified as Type 1 DM were,, included in a prospective, nation-wide population-based study. All patients were followed at local hospitals for examination of HbA(1c) and insulin d
Alphavirus glycoproteins have broad host ranges. Human immunodeficiency virus type 1 (HIV-1) vectors pseudotyped with their glycoproteins could extend the range of tissues that can be transduced in both humans and animal models. Here, we established stable producer cell lines for HIV vectors pseudotyped with alphavirus Ross River virus (RRV) and Semliki Forest virus (SFV) glycoproteins E2E1. RRV E
Proportionalitetsprincipen är en grundläggande rättsprincip som förekommer inom en rad rättsområden. Den är en viktig princip inom bland annat straffrätten. På det förvaltningsrättsliga området ses den som en allmänt tillämplig rättsprincip gällande utan lagstöd. Den finns dock även lagfäst i en rad lagar som polislagen och skatteförfarandelagen. Principens utveckling i svensk förvaltningsrätt harThe principle of proportionality is a fundamental principle of law that appears within a range of legal areas. It is an important principle in areas such as criminal law. Within the field of administrative law it is seen as a generally applicable principle of law, valid without legislative support. It is,also codified in a number of laws for example the police law and the tax procedure law. The P
