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Popular Abstract in Swedish Skador med avskärning av nerver i övre extremiteten drabbar oftast unga personer. Nervskadan medför ett betydande handikapp i form av förlorad känsel och muskelkontroll i armen och/eller handen. Vid en nervskada dör de delar av nervfibrerna (axonerna) som är belägna bortom avskärningen medan nervens stödjeceller och ytterhölje finns kvar. För att återfå funktion måste nA new and simple method for the repair of nerve defects, in which sutures alone are used to guide regeneration between the nerve endings, was developed. Bilateral seven to 17 mm rat sciatic nerve defects were bridged by continuous longitudinal sutures with or without different modifications, by conventional autologous nerve grafts or direct repair under tension as controls. Evaluation was performe

Popular Abstract in Swedish Bindväv är ett samlingsnamn för vävnader som ger form och struktur i olika organ i kroppen. I brosk och ben utgör bindväven hela eller stora delar av organet, medan i andra organ, t.ex. muskel, är bindväven endast en liten del. Bindväv karaktäriseras av ett nätverk av proteiner och polysackarider (extracellulär matrix), som omger och produceras av en relativt liten andeThis thesis describes the structure and interactions of a novel extracellular matrix protein - PRELP (proline arginine-rich end leucine-rich repeat protein). The amino acid sequence of PRELP showed that it belonged to the leucine-rich repeat (LRR) protein family in connective tissues. The main part of PRELP is composed of 10 LRRs flanked by disulfide bridges at the amino- and carboxy-terminal end

Popular Abstract in Swedish Denna studie behandlar krav som verksamhetens karaktär medför på ekonomisk styrning i social verksamhet inriktad mot barn och ungdomar. I kommuner finns flera verksamheter som bedriver ett omfattande arbete inriktat mot barn och ungdomar, t.ex. förskola, skola och socialtjänst. Många olika professionella aktörer är inblandade i arbetet med denna målgrupp, såsom förskollThe aim of this study is to contribute to an increased understanding of the demands that the operation’s character places on management control. The study’s point of departure is the assumption that management control must be adapted to the operation’s character in order to be able to support strategy implementation and the achievement of objectives (contingency theory). The study deals with the d

Popular Abstract in Swedish Monoaminer Adrenalin, noradrenalin, dopamine, serotonin och histamin är samtliga monoaminer som fungerar som signalsubstanser och hormoner. Monoaminer är viktiga i många fysiologiska processer och obalans i deras nivåer ger ett brett spektrum av störningar. De klassiska är: serotoninbrist som ger depression, ångest och sömnstörningar, dopaminbrist ger motoriska störninThe present study explored the gene and protein expression of the monoamine transporters in human endometrium throughout the menstrual cycle, in early decidua and in placentas from normal as well as preeclamptic pregnancies using in-situ hybridization, real time-PCR, immunohistochemistry and primary tissue cultures. Four distinguishable patterns were observed in the endometrium over the menstrual

Popular Abstract in Swedish En av de viktigaste frågeställningarna inom molekylär genetik är hur uttrycket av människans ca 30-40 000 gener regleras i tid och rum. En typ av reglering som är väldigt viktig är transkriptionell reglering och denna utövas av proteiner som kallas transkriptionsfaktorer. Dessa binder till specifika områden i DNA strängarna i närheten av genkodande regioner och kan däri

In the early 1990s, Indonesia was seen as one of the post war success stories. The country was boasting an impressive growth record and had seen the number of poor continuously decline. This picture of Indonesia stood in stark contrast to the situation only 30 years earlier when the economy was in a shambles and starvation was a real threat. At the core of this change in Indonesia lies the transfo

Popular Abstract in Swedish Det ljus (fotonflöde) som solen sänder ut är grunden för biologiskt liv. Med denna strålning överförs en del av den frigjorda energin från solen till jordens biosfär, där växterna tar upp de energirika fotonerna och omvandlar fotonenergin till kemisk energi. Den kemiska energin lagras sedan som energirika molekyler som transporteras runt i de biologiska systemen för attA low volume and long optical path spectroelectrochemical cell was constructed and tested in a number of applications such as detection of direct electron transfer (DET) between redox enzymes and gold electrodes, determination of the formal potentials of redox centres in proteins and enzymes, as well as mechanistic studies of heterogeneous and intermolecular electron transfer of copper oxidases an

Popular Abstract in Swedish Värmebehandling av livmoderslemhinnan med ballongkateter - en ny metod att behandla rikliga mensblödningar. Mera än 11% av svenska kvinnor besväras av rikliga menstruationer (menorrhagi). När läkemedelsbehandling mot menorrhagi inte hjälper kan livmodern opereras bort. Varje år, i Sverige, opereras livmodern bort hos 4-5000 kvinnor på grund av rikliga mensblödningar. DThermal endometrial destruction by means of a silicone balloon catheter is a new form of treatment for menorrhagia aimed at reducing menstrual blood loss. The purpose of the present work was to study, experimentally, the thermal effects on and the thermal conductivity of uterine tissue, to obtain a basis for the estimation of optimal treatment conditions by means of numerical analyses using a comp

Place-names often reflect local, cultural, and political history. It is only natural, therefore, that words for such historically important phenomena as boundaries should form part of place-names. In England, there is a fair number of place-name elements that refer to boundaries. Some of them are treated in this thesis. They are OE (ge)mǣre, OE mearc, OE *rān, *rǣn(e), ON rein, ON rá, and OE hār.

Objective: To investigate recent evidence suggesting that social factors are causally related to the development of schizophrenia. Method: I conducted a sytematic review of MEDLINE to identify possibly relevant studies. The search was limited to peer-reviewed studies and review articles appearing in English-language journals since 1996. Studies were included if they used standardized diagnostic cr

Aims and objectives. The aim of this study was to describe characteristics in burn injuries in children (zero to six years old), consulting primary care and hospital-based care in Malmo, Sweden. Burn-injured children consulting the University Hospital or the 21 Health Centres, during year 1998 and year 2002, were included. Background. Epidemiological studies of burns in children have mostly been h

Much of earlier work on predictive models for accidents has been focused on rural traffic or urban intersections. This work has aimed at identifying and investigating possible improvements to predictive models for accidents on urban links. A special focus has been on the accidents of vulnerable road users. The possible improvements investigated have been: a) the use of exposure data for vulnerabl

The topography of the antigen-binding site as well as the number and the positioning of the antigen contact residues are strongly correlated with the size of the antigen with which the antibody interacts. On the basis of these considerations, we have designed a focused scFv repertoire biased for haptens, designated the cavity library. The hapten-specific scFv, FITC8, was used as a scaffold for lib

Hepatitis B virus (HBV) has eight genotypes which have distinct geographical distributions. Studies comparing differences in the clinical outcomes of infections caused by strains with genotype-related variations in the HBV genome have largely compared genotypes B and C and genotypes A and D but not all four genotypes. The present study included 196 HBV-infected patients attending an infectious dis

The purpose of this gaper is to analyze and detect changes in body position (BPC) during electrocardiogram (ECG) recording. These changes are often manifested as shifts in the, electrical axis and may be misclassified as ischemic changes during. ambulatory monitoring. We investigate two ECG signal processing methods for detecting BPCs. Different schemes for feature extraction are used (spatial and

Guidelines are used in information and quality management systems to ensure high quality by supporting design, production and communication processes. These guidelines can be presented as a conventional system on an intranet suitable for printouts, visualized as a traditional text-based report with a list of headings accompanied by tables and pictures or presented as paper documents in manuals or

Do moor frog (Rana arvalis) and common frog (R. temporaria) tadpoles increase developmental rate if there is a risk of their pond drying up before metamorphosis? To study this, I performed an experiment designed to mimic natural conditions in many drying ponds. The number of tadpoles per tank was constant during the experiment but the water level was lowered in experimental tanks so that crowding

The effects of hypothermia on hypoglycemic brain damage were studied in rats after a 30-min period of hypoglycemic coma, defined as cessation of spontaneous EEG activity. The rats were either normothermic (37 degrees C) or moderately hypothermic (33 degrees C). Morphological brain damage was evaluated after various periods of recovery. Hypothermic animals with halothane anesthesia never resumed sp

OBJECTIVE: This study analyses the correlation between the Swedish underprivileged area score and sales of tranquillizers, hypnotics/sedatives, neuroleptics and antidepressants, and the correlation between these sales and mortality and suicide rates, with the aim of using sales data to identify areas with poor socioeconomic conditions. SETTING: Southern Sweden, 33 municipalities in Skane, 1987 and

Soft tissue sarcomas (STS) are a heterogeneous group of highly malignant mesenchymal tumors that account for ~1% of all malignancies. Frequent heterogeneity and pleomorphism along with suboptimal diagnostic reproducibility and insufficient prognostic markers make clinical management of these tumors difficult. This thesis has applied microarray-based gene expression and copy-number profiling to STS