Filtyp
Pancreastatin, a C-terminally amidated peptide derived from chromogranin A, is known to inhibit insulin secretion, pancreatic enzyme release, and gastric acid secretion. It also inhibits parathyroid hormone (PTH) secretion in animals. The physiologic and clinical relevance of pancreastatin in humans, however, is not known. Because pancreastatin has been found in parathyroid adenomas, we investigat
Stars in open clusters are expected to share an identical abundance pattern. Establishing the level of chemical homogeneity in a given open cluster deserves further study as it is the basis of the concept of chemical tagging to unravel the history of theMilkyWay.M67 is particularly interesting given its solar metallicity and age as well as being a dense cluster environment.We conducted a strictly
Background and purpose — The number of patients where shoulder hemiarthroplasty (SHA) is an option is still substantial. Descriptive analyses performed by the Swedish Shoulder Arthroplasty Registry (SSAR) showed that while patients receiving SHA designs, i.e. resurfacing hemi (RH) and stemmed hemi (SH), reported similar shoulder functionality and quality of life, the revision rate for RH (12%) was
BACKGROUND: There are limited data on the long-term outcome and on factors influencing the prognosis in patients with cerebellar infarcts treated with surgical decompression.METHODS: Thirty-two patients (age 64.3 ± 9.9 years) with expansive unilateral cerebellar infarcts were retrospectively evaluated. All patients were treated with ventriculostomy, suboccipital decompressive craniectomy and remov
Objective: To clarify the preclinical stage of Alzheimer’s disease by estimating when β-amyloid accumulation first becomes associated with changes in cognition. Methods: Here we studied a large group (N = 4432) of cognitively unimpaired individuals who were screened for inclusion in the A4 trial (age 65–85) to assess the effect of subthreshold levels of β-amyloid on cognition and to identify which
The work in this thesis was carried out to highlight important chemical pathways in skeletal mechanisms for the three smallest alcohol fuels (methanol, ethanol and npropanol), two representative fuel alkanes n-heptane and n-decane, and finally the biodiesel surrogates, methyl-decanoate, methyl-5-decenoate, and methyl-9-decenoate. This aim was set up to further the efforts of creating Computational
An optimal network design was carried out to prioritise the installation or refurbishment of greenhouse gas (GHG) monitoring stations around Africa. The network was optimised to reduce the uncertainty in emissions across three of the most important GHGs: CO2, CH4, and N2O. Optimal networks were derived using incremental optimisation of the percentage uncertainty reduction achieved by a Gaussian Ba
Purpose: We present a novel algorithm for computer simulation of breast anatomy for generation of anthropomorphic software breast phantoms. A realistic breast simulation is necessary for preclinical validation of volumetric imaging modalities.Methods: The anthropomorphic software breast phantom simulates the skin, regions of adipose and fibroglandular tissue, and the matrix of Cooper's ligaments a
The β-catenin/Wnt signaling pathway plays an important role in all stages of T cell development. Nemo-like kinase (NLK) is an evolutionary conserved serine/threonine kinase and a negative regulator of the Wnt signaling pathway. NLK can directly phosphorylate histone deacetylase 1 (HDAC1), as well as T cell factor/lymphoid enhancer-binding factor (TCF/LEF), causing subsequent repression of target g
Vad orsakar Parkinsons? – Genombrott tyder på att skadade proteiner rör sig mellan celler – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Vad orsakar Parkinsons? – Genombrott tyder på att skadade proteiner rör sig mellan celler 2011-01-19 ⚠️ Den här artikeln är mer än 5
Background: The orally active quinoline-3-carboxamide tasquinimod [ABR-215050; CAS number 254964-60-8), which currently is in a phase II-clinical trial in patients against metastatic prostate cancer, exhibits anti-tumor activity via inhibition of tumor angiogenesis in human and rodent tumors. To further explore the mode of action of tasquinimod, in vitro and in vivo experiments with gene microarra
In order to improve biological control of agricultural pests, it is fundamental to understand which factors influence the composition of natural enemies in agricultural landscapes. In this study, we aimed to understand how agricultural land use affects a number of different traits in ground beetle communities to better predict potential consequences of land-use change for ecosystem functioning. We
Familjecentrerad vård – tillräckligt bra för barnen? – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Familjecentrerad vård – tillräckligt bra för barnen? 2016-05-13 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Den 1 januari 2015 trädde
https://www.vetenskaphalsa.se/familjecentrerad-vard-tillrackligt-bra-for-barnen/ - 2026-06-21
The purpose of this thesis is double. First, it will be shown that a number of problems of the syntax of ancient, literary Italian lend themselves readily to an analysis in terms of the Theory of Principles and Parameters. Second, the Italian data, supported by comparative remarks on modern Romance and Germanic, confirm the essential correctness of one particular version of the above theory namely
We have developed a combinatory antibody-antigen microarray for direct screening of multiple single-chain fragment variable (scFv) clones with no need for pre-purification or enrichment before screening. The straightforward workflow allows for early selection of binders to predefined peptide and glycopeptide targets. A capture antibody is contact printed on microarray slides, side by side with the
Bakgrund: För att tillverkande företag skall kunna vara konkurrenskraftiga, så är det viktigt att kontinuerligt sträva efter att eliminera alla orsaker till slöseri. En av de verktyg som kan användas för att bekämpa slöseri är TPM, vilket huvudsakligen är ett strukturerat sätt för att öka företagets tillförlitlighet till sina maskiner och produktionseffektiviteten genom att förstärka företagets unBackground: In order for manufacturing companies to stay competitive today, it is important to continuously strive towards eliminating any sources of waste. One of the tools to address waste elimination is to work with Total Productive Maintenance (TPM), which essentially is a structured way of improving the company’s machine reliability and production effectiveness through enhancing the sites mai
Purpose: Study if and how personnel-intensity affects companies' post acquisition stock performance Methodology: Quantitative study of 90 american companies that in 2007 made acquisition deals worth over $100 MUSD. An event window of five days was used, and comparisons between industries were done to find correlation between personnel-intensity and performance. Theoretical Perspectives: Based
Skatteplanering genom så kallade räntesnurror har skapat snedvridningar inom bolagssektorn där företag med stora räntekostnader har kunnat minska den beskattningsbara vinsten genom avdrag. Avsaknaden av en tydlig reglering medförde att Skatteverket lade fram en promemoria år 2008 med förslag om en särskild reglering med begränsning av ränteavdrag som främst motiverades av skatteskäl. RänteavdragsbTax planning through interest deduction has created inequality on the market where companies with high interest cost have been able to reduce the taxable income through interest deduction. The lack of a clear regulation resulted in a memorandum from the Swedish Tax Authority presented in 2008 with the suggestion of a certain regulation with limitations regarding the possibility of interest deducti
Vid entreprenadarbeten kan skador uppstå på olika typer av egendom som inte tillhör själva entreprenadarbetena enligt entreprenadavtalet. Det är viktigt att en entreprenör kan överblicka vilka risker denne tar vid utförande av kontraktsarbeten, inte minst eftersom denne behöver teckna lämpliga försäkringar som täcker riskerna. Skador som drabbar entreprenörens avtalspart, dvs. beställaren, regleraIn relation to constructional work, a large variety of damages can occur on property that does not belong to the actual construction regulated in the contract between the contractor and the employer. Consequently, it constitutes a crucial matter that the contractor will be able to foresee the risks. This is important, especially considering appropriate insurances that the contractor needs to take
Enligt svensk rätt ska utländska äktenskap erkännas om de är giltiga enligt lagen i det land de ingåtts. Undantaget till detta är om äktenskapet går emot svensk ordre public. Huruvida så är fallet för polygami är fortfarande osäkert. Det här arbetet kommer inte beröra huruvida Sverige bör ha en begränsning på antal äktenskap eller inte, utan fokus ligger på den svenska hanteringen av utländska polAccording to Swedish law a foreign marriage is recognized if it is valid under the law of the state where it was entered into. The exception to this is if such a marriage is void as a matter of public policy. Whether or not that applies to polygamy is still uncertain. This thesis will not touch upon whether or not Sweden should have a restriction on the number of parties in a marriage; instead it
