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Objectives: The aim of this study was to evaluate the cost-utility of Docetaxel with doxorubicin and cyclophosphamide (TAC) and 5-fluorouracil, doxorubicin, cyclophosphamide (FAC) in node-positive breast cancer patients in the south of Iran. Methods: A double blind study was done on a cohort of 100 patients suffering from breast cancer with node-positive over 8 months in the radiotherapy center of

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Uppsatsen undersöker bolagsrevisorns externa skadeståndsansvar enligt 29 kap. 1–2 §§ aktiebolagslagen (2005:551). Då det externa ansvaret är fokus för uppsatsen behandlar uppsatsen skyddet för aktieägare och andra tredje män. Normskyddslärans betydelse för det externa skadeståndsansvaret är centralt för uppsatsen. I uppsatsen tillämpas en rättsdogmatisk metod. Metoden tillämpas då uppsatsen ämnar

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I den finansiella sektorn är en av de viktigaste aktiviteterna tillhandahållandet av betaltjänster. Som en konsekvens av genomförandet av Revised Payment Service Directive (PSD2), har fler aktörer kunnat erbjuda innovativa betaltjänster, bland annat tredjepartsleverantörer. Uppsatsen presenterar syftena med PSD2 och granskar kritiskt de konkurrensrättsliga effekterna direktivet haft i praktiken.

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In 2021, the EU announced the introduction of a carbon border adjustment mechanism (CBAM) to address the carbon leakage problem, which hampers its efforts to mitigate climate change. One of the CBAM requirements is that if an export party can provide that it paid for used carbon domestically, the corresponding amount will be deducted from the EU importers. After the announcement, Russia, one of th

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In the building industry, circular economy has gained much attention in recent years, yet thus far, little research has been conducted on the topic of intensified building use, despite the great potential this strategy offers in terms of emission reduction. One way of intensifying building use can be through the sharing of spaces among different users at different times. This thesis explores how m

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Against the backdrop of increasing global emphasis on environmental, social, and corporate governance (ESG), improving the efficiency of ESG data analysis and the sustainability of its sharing has become particularly important. This study proposes a comprehensive research framework, first demonstrating the advantages of deep models for ESG data analysis, and then discussing the combination of ESG

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This study is an initial attempt to investigate value co-creation in the gaming industry by looking at Value Co-Creation through a framework called The Value Co-Creation Egg. The aim of the framework was to identify the mechanisms of The Consumer and The Company, which ultimately led to a deeper understanding of how these actors operate within the context of The Market. To understand The Consumer,

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The plausibility threshold started, and is still, developing through the case law of the EPO. It is used as a tool against speculative patents, as the claimed technical effect of the invention must be made plausible. The plausibility threshold is foremost being used at the EPO in relation to the requirement of an inventive step under Article 56 EPC and the requirement of sufficiency of disclosure

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This Bachelor’s thesis is in collaboration with Saab Kockums AB. Saab Kockums develops and constructs marine technology, ships and submarines for civil and military use. In different development stages for systems to be implemented and built on ships, submarines or the like, different components such as sensors or information display systems need to be tested and functionality verified. For the sy

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År 2018 antog EU ett ändringsdirektiv vad gäller obligatoriskt automatiskt utbyte av upplysningar i fråga om beskattning, benämnt ”DAC 6”, med vilket ett regelverk om rapporteringspliktiga gränsöverskridande arrangemang införs. Genom detta ändringsdirektiv ålades medlemsstaterna att införa regler med vilka skatterådgivare, och i vissa fall skattebetalare, förpliktas att till behörig myndighet rappIn 2018 the EU adopted a Council Directive amending Directive 2011/16/EU as regards mandatory automatic exchange of information in the field of taxation, abbreviated as “DAC 6“, introducing a requirement to report to tax authorities specific cross-border arrangements. According to the amending Directive, the Member states were obliged to introduce regulation by which intermediaries, and in certain

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Warnings that the Swedish culture and popular education (folkbildning) infrastructure is under threat due to cutbacks in public funding have recently been highlighted in a joint report published by national interest organizations representing the library and popular education sector. This thesis seeks to explore the role and perceived value of the collaboration between study associations and publi

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This study examines how part-time work is discursively constructed and contested in the German political debate following the CDU's proposal to limit the right to part-time work in January 2026. Situated in the context of demographic change and labour shortages, the proposal frames part-time employment primarily as an economic burden – a framing that raises questions about how economic product

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This doctoral thesis has its theoretical origin in the notion that the information flow between management teams, financial analysts and investors is especially exposed to information asymmetry when knowledge-intense companies are concerned. Information asymmetry may aggravate agency problems and risk causing an impairment of the efficient allocation of capital on the stock market. Therefore, the

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Background. In a search for immunosuppressive drugs having novel mechanisms, monocarboxylate transporter (MCT-1) inhibitors were identified that markedly inhibited immune responses. Here, we report the effects of AR-C117977, a potent MCT-1 inhibitor, on alloimmune responses in the rat. Methods. In vitro activity was determined in a rat mixed lymphocyte response (MLR). In vivo activity was tested i

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Purpose - Considering the importance of supply chain integration (SCI) in literature and the increasing outsourcing of logistics, this paper aims to study the role of logistics service providers (LSPs) in supporting SCI and clients' performance.

Design/methodology/approach – This research is based on a two-step approach: a literature review on supply chain integration (SCI

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High throughput approaches such as whole genome sequencing (WGS) and whole exome sequencing (WES) create an unprecedented amount of data providing powerful resources for clinical care and research. Recently, WGS and WES services have been made available by commercial direct-to-consumer (DTC) companies. The DTC offer of genetic testing (GT) has already brought attention to potentially problematic i

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In the mid-twentieth century, Sweden distinguished itself as one of the most organized and participatory democracies in the world, with high levels of voting turnout and party membership. But in the late nineteenth century the situation was much the opposite – Sweden had for Western Europe a low degree of suffrage, and low political participation. To explain the turnaround, this paper explores e

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Incumbent firms face growing pressure to transform their business towards sustainability. However, business models for sustainability (BMfS) and circularity are grounded in fundamentally different institutional logic which, for incumbents, creates tensions with existing business models, structures and routines. How organizations manage tensions from conflicting logics is explored comprehensively i

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The article presents the main results of a joint investigation by Swedish researchers and industry representatives carried out during 2006-2007 concerning the benefits of modern object based information and communication technology, ICT, for industrialisation of the building industry. The background for the investigation was an experience by both parties of a lack of coherence between scientific r