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Importance: The lack of an in vivo measure for α-synuclein (α-syn) pathology until recently has limited thorough characterization of its brain atrophy pattern, especially during early disease stages. Objective: To assess the association of state-of-the-art cerebrospinal fluid (CSF) seed amplification assays (SAA) α-syn positivity (SAA α-syn+) with magnetic resonance imaging (MRI) structural measur
Many patients with serious illness struggle to talk about the possibility of dying; yet basic prognostic awareness is crucial for informed decision making. In this article, we aim to help outpatient clinicians working with seriously ill patients ambivalent, uncomfortable, or fearful of further discussion about the future. We describe a dual framework that focuses on living well while acknowledging
A small Mesolithic campsite near Sammakko in northernmost Sweden has been identified through its abundance of burnt bone and quartz refuse from stone tool manufacturing/ maintenance. Radiocarbon dating places hunter-gatherer activity here around 8900 years ago, 1800 years later than the oldest known settlement in Norrbotten, the Aareavaara site. Sediment stratigraphy in nearby lake basins suggests
Within the field of syntactic typology, which seeks to describe and classify the range of grammatical phenomena extant in the world’s languages, one of the most important problems is whether or not a given language is ergative. Within a generative approach, a further problem is accounting for the existence of ergative languages by the definition of what may be termed an ‘ergativity parameter’. Thi
OBJECTIVES: To investigate how the co-occurrence of diabetes, hypertension and overweight/obesity is associated with pain following an exercise intervention for knee and hip osteoarthritis (OA).METHODS: Register-based cohort study. We included people from the Swedish Osteoarthritis Register who underwent education and exercise for knee or hip OA. Diabetes and hypertension were defined using medica
This thesis discusses organizational communication in Sweden following a scandal. The communication is based on the period after the scandal has gained attention. The communication 2 is divided into formal and informal communication based on whether the organization or a third party controlled the channel of communication. The communication is analyzed through cases and takes into consideration th
This evaluation field study aims to study the LM International/Läkarmissionens and Adventist Development and Relief Agency (ADRA) Kenya’s project against Female Genital Mutilation/Cutting (FGM/C) in southwestern Kenya, a crime against human rights and a severe problem in parts of Kenya. The laws against FGM/C have had limited effect in the region, so the groundwork is more important than ever. The
With the emergence of COVID-19, various industries felt under the pressure from limitations associated with the pandemic and transition to a work-from-home workstyle. Healthcare and Software Development is one of the industries that had to face increased demand for their products and services under severe circumstances. As an interconnection of these spheres,eHealth had to address challenges that
This thesis explores how history is represented in the video game Ghost of Tsushima from 2020. The game is set on the island of Tsushima off the coast of Japan during the Mongol invasion of 1274. Players are placed into this world as the fictive samurai Jin Sakai, fighting to free the island from the Mongol yoke. At the same time the samurai is torn between following his family's code of honou
Over the years, flight safety has improved through reliable automated systems, but accidents still occur where pilots are faced with unexpected technical malfunctions without previous training. This thesis aimed to investigate possible ways to develop evidence-based training further to prepare pilots for managing unexpected events by identifying resilient promoting strategies applicable in daily f
Using Laclau’s and Mouffe’s discourse theory, this thesis examines how the discursive formation of ”immigrants” as a group has developed in the Swedish party leader debates of 2013 and 2017. During these years the number of immigrants had a record year and the conversation and politics on immigration changed drastically in Sweden. This thesis is used to find out if the discourse on the conversatio
Under #metoo-uppropet hösten 2017 uppmärksammades problematiken med sexuella trakasserier på arbetsplatsen. Missnöjet har föranlett frågan om det arbetsrättsliga skyddet mot sexuella trakasserier behöver ses över för att säkerställa ett effektivt skydd. Uppsatsen utreder gällande rätt med utgångspunkt i DL, AML samt LAS, för att sedermera konkretisera vilket typer av problem som kan identifieras iOne of the subjects of #metoo late 2017 was the problem of sexual harassment in the workplace. Questions were asked whether or not the current labor legislation could ensure sufficient protection against further sexual harassment. This thesis investigates the established law, more precisely The Discrimination Act (DL), The Work Environment Act (AML) and The Employment Protection Act (LAS), in orde
Fankulturen till pojkbandet One Direction har diskuterats flitigt i olika media där fansen, också kallade directioners, har blivit utmålade som galna och fanatiska. Denna (n)etnografiska studie undersöker hur dessa mediala berättelser påverkar fans i deras identitetsskapande samt påverkar deras deltagande i fankulturen. Uppsatsen analyserar också homoerotisk fanfiction skriven om bandet, som i deThe One Direction fandom has been a source for a lot of discussion in different media, where fans, also known as Directioners, have been viewed as crazy, fanatic and also said to send deaththreats. This (n)ethnographic study investigates how these media narratives shape fans in the formings of their identities, and also how it effects them when participating in the fandom. This study also analyse
Innovation is gospel today. This also means a surge in popularity for the agents behind innovation; innovators. But who are they, exactly? Anecdotal evidence from both recent times and historical settings tend to emphasize remarkable individuals, who more or less alone created amazing things. By utilizing the SWINNO-database of innovations, this thesis examines how empirically prevalent the narrat
This thesis investigates how Denmark, as a small Member State, was able to use its 2012 Presidency to exert significant influence and further its interests via the Energy Efficiency Directive. Denmark’s influence is puzzling for three reasons: Firstly, it goes against the literature’s expectations of a small Member State Presidency, which is supposed to work as an impartial chair. Secondly, ener
