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Cu3Sn - understanding the systematic absences.

The intermetallic compound Cu3Sn has previously been described as a long-period antiphase boundary superstructure of the Cu3Ti structure type. While the compound itself has been reported as a tenfold and an eightfold superstructure, ternary doped alloys show shorter repetitions. Interestingly, the diffraction patterns of these compounds show non-crystallographic absences that cannot be explained u

Meniscus pathology, osteoarthritis and the treatment controversy.

The menisci are internal structures that are of central importance for a healthy knee joint; they have a key role in the structural progression of knee osteoarthritis (OA), and the risk of the disease dramatically increases if they are damaged by injury or degenerative processes. Meniscus damage might be considered a signifying feature of incipient OA in middle-aged and elderly people. As approxim

New drugs in migraine treatment and prophylaxis: telcagepant and topiramate.

Although the triptan drugs provide effective relief from migraine for many patients, a substantial number of affected individuals are unresponsive to these compounds, and such therapy can also lead to a range of adverse effects. Telcagepant represents a new class of antimigraine drug-the calcitonin gene-related peptide receptor blockers. This compound exerts its effects by blocking receptors for t

Sensitizing capacity and cross-reactivity of phenyl glycidyl ether studied in the guinea-pig maximization test.

BACKGROUND: Simultaneous contact allergies to the reactive diluent phenyl glycidyl ether (PGE) and epoxy resins based on diglycidyl ether of bisphenol A (DGEBA) or epoxy resins of the bisphenol F-type have been reported. The latter epoxy resins contain three isomers of diglycidyl ether of bisphenol F (DGEBF). PGE, DGEBA, and DGEBF are chemically similar with respect to the reactive glycidyl group

Functional evaluation after rat sciatic nerve injury followed by hyperbaric oxygen treatment

Previous experimental studies have shown positive effects of hyperbaric oxygen treatment in the early regeneration phase in the first few days following a nerve injury. In this study, functional effects of hyperbaric oxygen treatment were studied in 2 series of rats after an injury to the sciatic nerve - a standardized crush injury and nerve transection and repair, respectively. Postoperatively th

Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis

Tissue factor (TF) is the cellular receptor for factor FVIIa (FVIIa), and the complex is the principal initiator of blood coagulation. The effects of FVIIa binding to TF on cell migration and signal transduction of human fibroblasts, which express high amounts of TF, were studied. Fibroblasts incubated with FVIIa migrated toward a concentration gradient of PDGF-BB at approximately 100 times lower

Parental level of anxiety, sense of coherence and state of mind when choroid plexus cysts have been identified at a routine ultrasound examination in the second trimester of pregnancy: a case control study.

The aim of the study was to compare parents' experience of a routine ultrasound examination in the second trimester, when a choroid plexus cyst/cysts (CPC) were found (Study group; n = 22), with matched controls where no fetal deviations were identified (Control group, n = 66). All the parents had participated in a larger cohort study. The instruments used for measuring anxiety were STAI-state/tra

Evolving strategies for software architecture and reuse

To achieve their business objectives, software developing companies employ different technical and managerial strategies concerning architecture and reuse. These strategies include component-based development, software platforms, product lines and highly configurable code bases. Frameworks for describing these strategies have recently emerged, presenting them in orders of increasing maturity, with

On a first-order stochastic differential equation

A first-order system with random parameters and random forcing is studied. The analysis is concentrated on the probability distributions. It is shown that considerable qualitative information can be obtained from Feller's classification of the singular points of the forward and backward Kolmogorov equations. It is found that there is a drastic difference between the cases of uncorrelated and stron

The Malmo model for immune tolerance induction: impact of previous treatment on outcome

Ten patients, who had been treated according to the Malmo model for immune tolerance induction (ITI), were analysed regarding treatment with clotting factors and chemotherapy during the time period between inhibitor detection and ITI. Of the patients who were successfully rendered tolerant (n=6) all but one had received treatment with FVIII, either alone (n=1), or combined with cyclophosphamide (n

A cognitive endophenotype of autism in families with multiple incidence

Twin and family studies have established that there is a strong genetic basis for autism spectrum disorders. To facilitate the identification of susceptibility genes and to study pathways from gene-brain to cognition a more refined endophenotype-based approach may be useful. The purpose of the present study was to examine the neurocognitive endophenotype of autism, in families with multiple incide

Owners of the Past: Readbacks or Tradition in Mi'kmaq Narratives

When the ethnographer Wilson Wallis did his first fieldwork among the Canadian Mi’kmaq Indians 1911, one recurrent character in their oral tradition was the traditional culture hero Kluskap. When Wallis returned to Nova Scotia in 1953 he found that not many Mi’kmaq in the thirties had heard about Kluskap, and if they had, it was through books or the television series “The Adventures of Glooscap”.

Taxation of Dividend Income and Economic Growth: The Case of Europe

More recently researchers have turned to analyze how the tax structure, rather than the overall tax level, affects economic performance. For instance, several papers have investigated how taxation on corporate and individual (labor) income influences growth. Taxation of dividend income may also influence growth via its impact on investments and firm behavior. Within the academic community there is

Taking pedagogic responsibility for the difference between plagiarism and cheating

The Swedish Higher Education Ordinance states1 in Chapter 8, section 1 (Svensk Förfat- tningssamling [SFS] 1993:100) that disciplinary action can be taken against a student who “at- tempt to deceive during examinations or when academic work is otherwise assessed”. Suspicion of such behaviour is to be reported to the disciplinary board, which in turn has to establish the students intent. The main f

Value and Risk: Enterprise Risk Management in Statoil

In Statoil, understanding and managing risk is today considered a core value. This principle has been duly integrated in the organization, and is inscribed in steering documents as well as in a booklet handed out to all employees, describing core values, corporate governance, the operating model and corporate policies. The company has developed a sophisticated approach to ERM that centers on the p

Study of the sequential constraint-handling technique for evolutionary optimization with application to structural problems

Engineering design problems are most frequently charac-terized by constraints that make them hard to solve and time-consuming. When evolutionary algorithms are used to solve these problems, constraints are often handled with the generic weighted sum method or with techniques specific to the prob-lem at hand. Most commonly, all constraints are evaluated at each generation, and it is also necessary