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This paper examines governance responses to Mobility as a Service (MaaS). The analysis focuses on the interactions between public transport systems and MaaS developments in Amsterdam, Birmingham, and Helsinki. Case comparison is informed by the multilevel perspective on socio-technical transitions and literature on meta-governance of networks. Drawing on these frameworks and empirical findings, th
A field study on current structure and circulation characteristics in Lake Vendyurskoe, a small, shallow, icecovered lake in Karelia, Russia, is presented. The current velocity magnitudes were generally found to be small. The most pronounced currents had an oscillating character, with velocity amplitudes on the order of millimeters per second. The oscillation period, obtained from spectral density
This paper adds to the small literature on the role of welfare benefits and mental health by studying the relationship between uptake of Social Assistance Benefit (SAB) and objective mental health measures. We use rich longitudinal administrative data on income, unemployment benefits and psychopharmaceutic prescriptions (antidepressants, anxiolytics, and hypnotics) for more than 140,000 Swedes in
The study of early watermills has, from its very beginning, concentrated on two issues: their diffusion (in time and space) and their technical construction. Very little interest has been devoted to the persons who built and managed them—the millwrights and the millers. This tendency has been even more manifest from the 1980s onward, when interest has focused more and more on the increasing number
This study investigates the selection into lab experiments among university students based on data from two cohorts of a university’s first-year students. The analysis combines two experiments: a classroom experiment in which we elicited measures for risk, time, social preferences, confidence, and cognitive skills using standard measures from the experimental literature; and a recruitment experime
The procedure of aligning a positron emission tomography (PET) image with a common coordinate system, spatial normalization, typically demands a corresponding structural magnetic resonance (MR) image. However, MR imaging is not always available or feasible for the subject, which calls for enabling spatial normalization without MR, MR-less spatial normalization. In this work, we propose a template-
Diluting the combustion mixtures is one of the advanced approaches to reduce the NOx emission of methane/air premixed turbulent flame, especially with high diluents to create a distributed reaction zone and mild combustion, which can lower the temperature of reaction zone and reduce the formation of NOx. The effect of N2/CO2 dilution on the combustion characteristics of methane/air premixed turbul
We present the results of dynamic in-situ 3D X-ray imaging of methane hydrates microstructure during methane hydrate formation and dissociation in sand samples. Short scanning times and high resolution provided by synchrotron X-rays allowed for better understanding of water movement and different types of gas-hydrate formation. Complementing previous observations, we conclude that the process of g
The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. Two of the f
Bridges are subject to a plethora of deterioration phenomena, such as corrosion, fatigue, and damaging events (e.g., truck impacts and earthquakes) that can affect their performance and compromise functionality and safety. These challenges, along with the expansion of physical infrastructures and limited economic resources, underscore the need for effective management systems to enhance the effici
Confinement of reactants within nanoscale spaces of low-dimensional materials has been shown to provide reorientation of strained reactants or stabilization of unstable reactants for synthesis of molecules and tuning of chemical reactivity. While few studies have reported chemistry within zero-dimensional pores and one-dimensional nanotubes, organic reactions in confined spaces between two-dimensi
This paper aims to contribute to the field of policy enactment studies with a deepened understanding of the significance of the students when a pedagogical vision is enacted. The paper is based on a single case study using observations, surveys, interviews, and document studies. Informed by policy enactment theory, we analyse the students’ role in enacting the vision at the newly established Newsc
Rieger syndrome is an autosomal dominant human disorder affecting eye, tooth and umbilical development, andwhose primary morbidity is the 50% occurrence of glaucoma in affected individuals. The identification of etiologicmutations in the PITX2 gene and its encoded protein, solurshin, inspired the development of a transgenic animal thatmight serve as a model for this disorder. In addition, the more
Recent research indicates that there is a gap in life expectancy between the rich and the poor. This raises the question: should we on egalitarian grounds use income-based equity weights when we assess benefits of alternative benevolent interventions, so that health benefits to the poor count for more? This article provides three egalitarian arguments for using income-based equity weights under ce
The ALICE Collaboration reports a search for jet quenching effects in high-multiplicity (HM) proton-proton collisions at s = 13 TeV, using the semi-inclusive azimuthal-difference distribution ∆φ of charged-particle jets recoiling from a high transverse momentum (high-pT,trig) trigger hadron. Jet quenching may broaden the ∆φ distribution measured in HM events compared to that in minimum bias (MB) e
Hypomethylating agents (HMAs) are frontline therapies for Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are commonplace. To address this, we perform a genome-wide CRISPR-Cas9 screen in a human MDS-derived cell line, MDS-L, and identify TOPORS as a loss-of-function target that synergizes with HMAs, reducing leukemic burden and i
At the end of September, David Malpass, the president of the World Bank, was heavily criticized after failing to acknowledge anthropogenic climate change [henceforth called climate change (1)]. Although he later apologized for and revised his remarks, they sparked a renewed public debate on the existence of climate changedeniers and their impact on our transition toward a more sustainable future (
