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The present study numerically investigates the second law analysis of turbulent flow in novel outward helical corrugated tubes by using a Reynolds Stress Model (RSM). A case of a transverse corrugated tube and five cases of helical corrugated tubes with different height-to-diameter ratios and pitch-to-diameter ratios are examined with Reynolds number ranging from 3800 to 43,800 at a constant wall
Under changing climate conditions, acceptable functionality of buildings and their adaptation to climate are required. More rain and extreme conditions in future make buildings and the built environment more vulnerable. There are currently several scenarios regarding possible future climatic conditions. Results from the impact analysis of climate change can be significantly affected by the selecte
Background: Despite the theoretical links between eating disorders and perfectionism, the definition of perfectionism in practice is complicated. The present study explored descriptions and experiences of perfectionism described by a transdiagnostic sample of patients. Methods: In-depth, semi-structured interviews were carried out with 15 patients. The interviews were analyzed by Thematic Analysis
Health related quality of life (HRQoL) is negatively impacted in patients suffering from Parkinson's disease (PD). For the specific components that comprise HRQoL, the relationship between clinical variables, such as disease duration, is not fully characterized. In this cross-sectional study (n = 302), self-reported HRQoL on the Parkinson's Disease Questionnaire (PDQ-39) was evaluated as a global
It has been suggested that inflammation related to intracerebral transplantation surgery can affect the survival of intrastriatal neural allografts. To test this hypothesis, we transplanted dissociated embryonic mesencephalic tissue from one of two rat strains, Lewis (allogeneic grafts) or Sprague-Dawley (syngeneic grafts), to the striatum of Sprague-Dawley rats. The target striatum was either int
Previous findings suggest a link between neuroinflammatory processes and suicidality. Despite several lines of evidence supporting this link, including increased pro-inflammatory markers in blood-, cerebrospinal fluid (CSF)- and in post-mortem brain samples from suicidal individuals, the underlying mechanisms remain poorly understood. In this pilot study, we explored the possibility that autoimmun
Primary hyperparathyroidism (pHPT) is associated with a right-shifted relation between parathyroid hormone (PTH) secretion and calcium. However, it is also possible that a decreased suppressibility of PTH secretion by calcium is important for maintaining hypercalcemia in pHPT. We therefore compared the suppression of serum levels of intact PTH induced by a 1.5-gram oral calcium load in patients wi
Effective material parameters for diffusion and elastic deformation are calculatedfor porous materials using a continuum theory-based superposition procedure. The theory that is limited to two-dimensional cases, requires that the pores are sufficiently sparse. The methodleads to simple manual calculations that can be performed by, e.g. hospital staff at clinicaldiagnoses of bone deceases that invo
The advent of inexpensive consumer virtual reality equipment enables many more researchers to study perception with naturally moving observers. One such system, the HTC Vive, offers a large field-of-view, high-resolution head mounted display together with a room-scale tracking system for less than a thousand U.S. dollars. If the position and orientation tracking of this system is of sufficient acc
While smoking is a well-established risk factor for pancreatic cancer, the effect of smokeless tobacco is less well understood. We used pooled individual data from the Swedish Collaboration on Health Effects of Snus Use to assess the association between Swedish snus use and the risk of pancreatic cancer. A total of 424,152 male participants from nine cohort studies were followed up for risk of pan
It is often claimed that the social sciences cannot be reduced to a lower-level individualistic science. The standard argument for this position (usually labelled explanatory holism) is the Fodorian multiple realizability argument. Its defenders endorse token-token(s) identities between “higher-level” social objects and pluralities/sums of “lower-level” individuals (a position traditionally called
Growing concerns regarding the vulnerability of communities to natural disasters and climate-related hazards and risks have caused attention to be increasingly directed towards adaptation and resilience as important policy prescriptions. These two concepts are commonly becoming normative when used in this context and seen as intrinsically linked to each other, i.e. adaptation leads to resilience a
ELT science drivers stress aperture, Strehl ratio, PSF definition andstability, field of view, wavelength range, flexibility, lowpolarisation and thermal emittance, auxiliary instruments, site andinfrastructure. Applicable science categories are planets and planetarysystems, stars and stellar systems, galaxies and galaxy clusters, andcosmology. ELT observations are needed for our own and other pla
In the present paper an iterative time-reversal algorithm, that retrofocuses an acoustic wave field to its controllable part is established. For a fixed temporal support, i.e., transducer excitation time, the algorithm generates an optimal retrofocusing in the least-squares sense. Thus the iterative time-reversal algorithm reduces the temporal support of the excitation from the requirement of neglig
The proteolytic caspase cascade plays a central role in the signaling and execution steps of apoptosis. This study investigated the activation of different caspases in apoptosis induced by MAL (a folding variant of human alpha-lactalbumin) isolated from human milk. Our results show that the caspase-3-like enzymes, and to a lesser extent the caspase-6-like enzymes, were activated in Jurkat and A549
