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This report looks at different methods of active teaching and learning and the application of these methods at the partner universities of the SPIDER project. Different methods of on-campus and online teaching are presented and reports on experiences in their application at the partner universities are discussed. In combination with the results from Intellectual Output (IO) 4, this results in best

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Background: Increasing carbon stock in standing forests is one of the proposed ways to mitigate climate change. However, in production forests, this typically would lead to reduced harvesting possibilities and thus reduced financial gain for the forest owners. The size of this reduction should depend on the chosen target level of the carbon stock as well as the required speed of accumulation. Furt

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In recent years, shared freight systems have emerged in many cities as a new modality of freight transportation. However, little attention has been paid to the impact of a city's socioeconomic status on the characteristics of a shared freight network. To fill this gap, in this study, the structural characteristics of an intra-urban shared freight network are measured from the perspective of comple

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The individual- and patch-based peatland-vegetation model LPJ-GUESS was employed to study past and future peatland carbon dynamics across the pan-Arctic. A substantial reduction in peatland sink capacity, expected under rapid global warming, has the potential to trigger important climate feedbacks.

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Breathlessness is a centrally processed symptom, as evidenced by activation of distinct brain regions such as the insular cortex and amygdala, during the anticipation and/or perception of breathlessness. Inhaled L-menthol or blowing cool air to the face/nose, both selective trigeminal nerve (TGN) stimulants, relieve breathlessness without concurrent improvements in physiological outcomes (e.g., br

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Observed winter near-surface air temperature anomalies in the Northern Hemisphere have exhibited a warm Arctic-cold Eurasia (WACE) pattern with interdecadal variation in recent decades, but the exact mechanism behind WACE is still under debate. This study used reanalysis data and climate model simulations to investigate the interdecadal variability of the WACE pattern on a centennial scale, as wel

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Complex diseases are caused by a combination of genetic, lifestyle, and environmental factors and comprise common noncommunicable diseases, including allergies, cardiovascular disease, and psychiatric and metabolic disorders. More than 25% of Europeans suffer from a complex disease, and together these diseases account for 70% of all deaths. The use of genomic, molecular, or imaging data to develop

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The influence of a quadrupole pair interaction on Kπ = 1+ states in rare earth nuclei is investigated using the Quasiparticle Random Phase Approximation. Comparison of the obtained results with available experimental data indicates a rather weak quadrupole pair interaction in these nuclei. The calculation of the B(M1) strength is extended to higher energies to account for the recently observed hig

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Genetic variation at the MTIF3 (Mitochondrial Translational Initiation Factor 3) locus has been robustly associated with obesity in humans, but the functional basis behind this association is not known. Here, we applied luciferase reporter assay to map potential functional variants in the haplotype block tagged by rs1885988 and used CRISPR-Cas9 to edit the potential functional variants to confirm

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Aims/hypothesisPPARGC1A encodes peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipocyte bi

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The expanded version of the Inventory of Depression and Anxiety Symptoms (IDAS-II) is a self-report measure of 18 empirically derived internalizing symptom dimensions. The measure has shown good psychometric properties in adults but has never been evaluated in children and adolescents. A Swedish version of the IDAS-II was administered to 633 children and adolescents (Mage =16.6 [SD = 2.0]) and 203

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Urbanization is not only a concentration of humans in city areas but also, the consumption and production activities that are comprised in urban space. In this sense, goods and services are developed through the urban economic actors, through labor, economic diversity, and prosperity. This article reviews the relationship between urban economics and tradesmen & craftsmen (TC). The focus is on

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Permafrost-affected ecosystems are subject to warming and thawing, which can increase the availability of subsurface nitrogen (N) with consequences in otherwise N-limited tundra and alpine vegetation. Here, we quantify the extent of warming and permafrost thawing and the corresponding effects on nitrogen availability and plant growth based on a 20-year survey across 14 sites on the Tibetan Plateau

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Accurate monitoring of the spatiotemporal variations in the gross primary productivity (GPP) in coastal wetlands is essential for blue carbon quantification. However, the currently available moderate-spatial-resolution GPP algorithms and products may contain large uncertainties and may rarely meet the demands of tidal wetland research. In this paper, we examine two statistical methods, namely, sim

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The Arctic temperature changes are closely linked to midlatitude weather variability and extreme events, which has attracted much attention in recent decades. Syntheses of proxy data from poleward of 60g gN indicate that there was asymmetric cooling of-1.54 and-0.61gg C for the Atlantic Arctic and the Pacific Arctic during the Holocene, respectively. We also present a similar consistent cooling pa

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Aeolian sand significantly affects permafrost degradation, but the effect of the aeolian sand on the permafrost on the Qinghai-Tibet Plateau remains unknown. The sand layer thickness is critical to its role. However, little quantitative research has been conducted on the effect of the sand layer thickness on its role. In this study, using CoupModel, we investigated the differences in the impact of

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Erosion and infrastructure in the Arctic can change the thickness of the active layer which can subsequently alternate the thermal-hydrological regime and change the drainage patterns on slopes. Previous studies have shown that drainage can either decrease due to the movement of water occurring in deeper soil layers with lower permeability or increase due to the formation of features like gullies

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Reliable quantitative vegetation reconstructions for Europe during the Holocene are crucial to improving our understanding of landscape dynamics, making it possible to assess the past effects of environmental variables and land-use change on ecosystems and biodiversity, and mitigating their effects in the future. We present here the most spatially extensive and temporally continuous pollen-based r

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In several large recent observational studies, peripheral arterial disease (PAD) was present in up to 50% of the patients with a diabetic foot ulcer and was an independent risk factor for amputation. The International Working Group on the Diabetic Foot therefore established a multidisciplinary working group to evaluate the effectiveness of revascularization of the ulcerated foot in patients with d

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Although Arctic tundra has been estimated to cover only 8% of the global land surface, the large and potentially labile carbon pools currently stored in tundra soils have the potential for large emissions of carbon (C) under a warming climate. These emissions as radiatively active greenhouse gases in the form of both CO2 and CH4 could amplify global warming. Given the potential sensitivity of thes